Washington Post art. today on NIH trial with "SLEEN"

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sailbd
Posts: 52
Joined: Thu Jan 27, 2011 10:58 am

Washington Post art. today on NIH trial with "SLEEN"

Postby sailbd » Tue Jun 05, 2018 4:11 pm

Hello everyone:
I saw an uplifting article in the Washington Post today regarding advances in adoptive cell therapy, including tumor-infiltrating lymphocytes (TILs as we know it) at NIH. Sorry - I don't know how to link the article.

But, guess what? Our very own Sleen (Celine) is named in the article as being the "first successful targeting of a deadly mutation called KRAS, which is implicated not only in colon cancers but in pancreatic and lung cancers". Incredible result with dramatic future implications.

I literally remember when Celine started her posts regarding this trial, and she was thoughtful and gracious during an incredibly difficult and uncertain time to take us on her journey through the process via her posts. (See her Topic posts). So, congratulations for being NED and thank you, Celine, for partaking in the clinical trial that will hopefully lead to developments that will bring relief to hundreds of thousands of people in the future!

Beckster
Posts: 258
Joined: Thu Jan 12, 2017 3:01 pm
Location: New Jersey

Re: Washington Post art. today on NIH trial with "SLEEN"

Postby Beckster » Tue Jun 05, 2018 4:33 pm

Thanks for sharing..... here is the link to the article: https://www.washingtonpost.com/national ... 8791294be9
57/Female
DX:(CC) 10/19/16
11/4/16- Lap right hemi(cecum)
CEA- Pre Op (1.9), Pre Chemo (2.5)
Tumor type: Adenocarcinoma
Tumor size: 3.5 cm x 2.5 x 0.7 cm
Tumor grade: G3 (surgical) G2 (pre-op)
TNM: T3N0M0/IIA
lymph nodes: 0/24
LVI present
Surgical margins: clear
MSS
12/27/2016 - Capeox, anaphylactic reaction to oxaliplatin on first infusion-discontinued
1/2/17 to 6/9/17- Xeloda monotherapy
6/26/17, 12/12/17, 6/18/17 CT Scan NED :D
CEA- 6/17- 3.6, 9/17- 2.8 12/17-2.8, 3/17-3.1, 6/17-3.0
Clear Colonoscopy 10/17 :D

NHMike
Posts: 1438
Joined: Fri Jul 21, 2017 3:43 am

Re: Washington Post art. today on NIH trial with "SLEEN"

Postby NHMike » Tue Jun 05, 2018 4:43 pm

Nice to see the article and the successes to date.
6/17: ER rectal bleeding; Colonoscopy
7/17: Stage 3B rectal. T3N1bM0. 5.2 x 4.5 x 4.3 cm. Lymphs: 6 x 4 mm, 8 x 6, 5 x 5
7/17-9/17: Xeloda +radiation
7/5: CEA 2.7; 8/16: 1.9; 9/8: 1.8; 11/30: 0.6; 12/20 1.4; 1/10 1.8; 1/31 2.2; 2/28 2.6; 4/10 2.8
MSS, KRAS G12D
10/17: 2.7 x 2.2 x 1.6 cm (-90%). Lymphs: 3 x 3 mm (-62.5%), 4 x 3 (-75%), 5 x 3 (-40%). 5.1 CM from AV
10/17: LAR, Temp Ileostomy, Path Complete Response
CapeOx 8 cycles 12/17-6/18

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Sleen
Posts: 310
Joined: Tue Jan 14, 2014 7:41 am
Location: Detroit
Contact:

Re: Washington Post art. today on NIH trial with "SLEEN"

Postby Sleen » Wed Jun 06, 2018 10:19 am

Thank you for your kind words, sailbd! I was very happily surprised to see the story.
I hope that many more people's stories like it will be written.

Celine
my blog: Cancer Riot

NED since April 2016!
April 2016: lower left lung lobectomy. NED
8 mo. f/u: 1 of 7 tumors progressed.
6 mo. f/u PR confirmed (Jan 2016)
Jul 2015: NIH TIL trial NCT01174121 NCI/NIH Surgery Branch FAQ
Dec 2015 stage IV w/bilateral lung mets
FOLFOX + Radiation (bladder)
KRAS G12D :: MSS
dx Sep 2013 @47yo: IIIc T4b N2b MX [bladder invasion, 17/21 lymph nodes]

Married 28 yrs. kids: 22, 19, 15, 11, 9
SE Michigan home schooler, unemployed mechanical engineer, and programmer.

sailbd
Posts: 52
Joined: Thu Jan 27, 2011 10:58 am

Re: Washington Post art. today on NIH trial with "SLEEN"

Postby sailbd » Wed Jun 06, 2018 4:54 pm

CBS' version of the same clinical trial:

https://nypost.com/2018/06/06/cancer-pa ... treatment/


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