Jack&KatiesMommy wrote:...my CEA is very sensitive and very reliable as an indicator of cancer for....years
My wife's CEA is a good marker until it flatlines near its historical baselines. But we got a slowly rising tide off AFP that doubled more than five times during off-and-on pill/IV C reductions. We get roller coaster action off CA199 with treatment changes that no longer go back to baseline on chemo + reduced supplements. The big deal is that we can stop and partly reverse them by adding mild or healthful things to immunochemo that already has components that have been (earlier) used to treat cancers associated with those markers.
A number of Erbitux patients have had dramatic CEA responses but then turned out to have non CEA cancer cells too, or develop unmonitored marker expressions. We reject the lack of extra markers monitoring approach for mCRC.
Of course, there are a lot of oncologists that will tell you CA199 and AFP are not a lot of things for CRC. They would have been my wife's bad luck...
PS rp1954...I am not sure what my other number mean.
MCV: 95.7 H 95.9 H 96.9 H
You'll have MCV in all CBC tests. The peaks and valleys, rises and declines, at dx; before, during, and after treatments have broad chemo activity meanings that we can compare with papers here.
LDH: 5/3/18: 182. 5/25/18: 172 6/21/18: 189
These are in the lowest range of LDH values for mCRC that maybe higher and more meaningful with KRAS mutants and CA199 above CRC medians at dx (~19). This is about mid range for "normal people".
My CEA has been such a great marker...showing cancer many months before we could ever find something on even a PET scan.
They do not test my CA199
The first test level is usually one of the most important ones. For 7-10% of CRC patients, serum CA199 is totally useless after the first value. For everybody else, it has potential uses.