Lung mets after HIPEC

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AJQ
Posts: 25
Joined: Sun Jul 16, 2017 9:29 am
Location: CA

Lung mets after HIPEC

Postby AJQ » Mon Apr 09, 2018 10:27 pm

Hello friends,

I have not posted for a while as I was recovering from HIPEC and then started working full time. Had my scan on Jan 30th this year which showed 2 lung nodules (6mm, 2mm). I am on watch and wait and my next scan is in 2 weeks.
so far I feel OK with the exception of some leg weakness and little shortness of breath.

Anyone with similar lung mets from Colorectal cancer? I would appreciate sharing your experience, symptoms and recommendations.
I am looking at all options, SBRT, Chemo and immunotherapy.

Thankx
AJ
53 yr, stage III adenocarcinoma of appendix(PD) and Cecum
5/16/17: LAP Appendix Removal
5/22/17: Diagnosed. T4 poorly differentiated with LVI
6/21/17: LAP RHC: 1/21 positive Lymph. T4N1M0
CEA 6/17: 1.0, 7/17: 1.0, 8/17: 1.0, 9/17: 2.0, 9/28: 2.0, 10/12: 1
7/27/17: started Xelox (Capox) cycles
10/17: CT scan. Multiple Peri and Pelvis mets
11/17: CRS/HIPEC. All nodules removed- low PCI
1/18: CT. 2 lung nodules. next CT on 4/24

User avatar
Atoq
Posts: 314
Joined: Wed Oct 25, 2017 9:31 am

Re: Lung mets after HIPEC

Postby Atoq » Tue Apr 10, 2018 7:20 am

Hi,
I have a metastasis in one lung, it was already there at diagnosis in October and had a diameter of 0.8 cm. One month ago, after removal of the main tumor, they took a core needle biopsy and determined that it is a metastasis from CRC and decided to wait three months before taking a new CAT scan and, if it is still solitary, remove it. What they told me is that these metastases grow quite slowly and do not produce new metastases, so it was better to wait before doing a VATS wedge surgery, so that we give some time to other metastases that might be present, to show up on the CAT scan.

All the best

Claudia
45 year old, mother of 2
Dx rectal cancer October 2017
At least T3N2aMX (suspect metastasis to one lung 8 mm)
Lynch negative
CEA 1.8
Neoadjuvant chemoradiotherapy Xeloda + 25x2 Gy
05.12.17 laparotomic surgery for blockage, colostomy
25.01.18 laparotomic lar, hysterectomy, ileostomy
05.03.18 core needle biopsy of lung, updated to stage IV
07.05.18 CAT scan, lung metastasis 11 mm
04.06.18 ileostomy reversal
26.06.18 wedge VATS surgery
24.08.18 CAT scan, clear
12.09.18 scope, ok. CEA 1.6

User avatar
Atoq
Posts: 314
Joined: Wed Oct 25, 2017 9:31 am

Re: Lung mets after HIPEC

Postby Atoq » Tue Apr 10, 2018 10:43 am

I forgot to say that when they are so small they do not give any simptoms.

Claudia
45 year old, mother of 2
Dx rectal cancer October 2017
At least T3N2aMX (suspect metastasis to one lung 8 mm)
Lynch negative
CEA 1.8
Neoadjuvant chemoradiotherapy Xeloda + 25x2 Gy
05.12.17 laparotomic surgery for blockage, colostomy
25.01.18 laparotomic lar, hysterectomy, ileostomy
05.03.18 core needle biopsy of lung, updated to stage IV
07.05.18 CAT scan, lung metastasis 11 mm
04.06.18 ileostomy reversal
26.06.18 wedge VATS surgery
24.08.18 CAT scan, clear
12.09.18 scope, ok. CEA 1.6

AJQ
Posts: 25
Joined: Sun Jul 16, 2017 9:29 am
Location: CA

Re: Lung mets after HIPEC

Postby AJQ » Tue Apr 10, 2018 2:11 pm

Atoq wrote:Hi,
I have a metastasis in one lung, it was already there at diagnosis in October and had a diameter of 0.8 cm. One month ago, after removal of the main tumor, they took a core needle biopsy and determined that it is a metastasis from CRC and decided to wait three months before taking a new CAT scan and, if it is still solitary, remove it. What they told me is that these metastases grow quite slowly and do not produce new metastases, so it was better to wait before doing a VATS wedge surgery, so that we give some time to other metastases that might be present, to show up on the CAT scan.

All the best

Claudia


Hi Claudia,

Thank you. This is very helpful and inline with what my docs said. The nodules are so small they want to wait and see if they grow and remain only two then they recommended SBRT.

AJ
53 yr, stage III adenocarcinoma of appendix(PD) and Cecum
5/16/17: LAP Appendix Removal
5/22/17: Diagnosed. T4 poorly differentiated with LVI
6/21/17: LAP RHC: 1/21 positive Lymph. T4N1M0
CEA 6/17: 1.0, 7/17: 1.0, 8/17: 1.0, 9/17: 2.0, 9/28: 2.0, 10/12: 1
7/27/17: started Xelox (Capox) cycles
10/17: CT scan. Multiple Peri and Pelvis mets
11/17: CRS/HIPEC. All nodules removed- low PCI
1/18: CT. 2 lung nodules. next CT on 4/24

User avatar
bitchslapped
Posts: 1483
Joined: Tue Sep 09, 2014 3:23 pm
Location: PNW/USA

Re: Lung mets after HIPEC

Postby bitchslapped » Sat Jun 16, 2018 1:50 pm

AJQ wrote: I am on watch and wait and my next scan is in 2 weeks.


AJ, Did scan reveal anything more? There is a lot on this site re: lung thangs; in fact there was a thread titled "Lung Thang Gang" if I remember correctly, but i couldn't find it through search box. But like I said, you don't have to look far on this site to find information.

How about an update when you get around to it?

Best Wishes
BS
DSS,35YO,unresect mCRC DX 7/'14,lvr,LN,peri,rib
FOLFOX+Avstn 4 Rnds d/c 10/'14
Stent 9/'14
FOLFIRI+Avstn 10/'14
Gone From My Sight 2/20/15
Me:garden variety polyps + precancerous polyp
Carergver x2 DH,DM dbl occupancy,'03-'10
DH dx 47YO mCRC,'04-'07 fried x HAI
DM dx CC 85YO,CC,CHF,stroke,dementia,aphasia

AJQ
Posts: 25
Joined: Sun Jul 16, 2017 9:29 am
Location: CA

Re: Lung mets after HIPEC

Postby AJQ » Sat Jun 16, 2018 3:03 pm

bitchslapped wrote:
AJQ wrote: I am on watch and wait and my next scan is in 2 weeks.


AJ, Did scan reveal anything more? There is a lot on this site re: lung thangs; in fact there was a thread titled "Lung Thang Gang" if I remember correctly, but i couldn't find it through search box. But like I said, you don't have to look far on this site to find information.

How about an update when you get around to it?

Best Wishes
BS



Hello Bitchslapped -
April scan revealed few more in the same lung but small. I am on an interesting targeted therapy( pill form) that is given to me as I match one of the amplification based on foundation tumor report. Also on light doze of Xeloda pills
There is hope and so far feeling ok.

Next scan in July

How is your friend doing?


AJ
53 yr, stage III adenocarcinoma of appendix(PD) and Cecum
5/16/17: LAP Appendix Removal
5/22/17: Diagnosed. T4 poorly differentiated with LVI
6/21/17: LAP RHC: 1/21 positive Lymph. T4N1M0
CEA 6/17: 1.0, 7/17: 1.0, 8/17: 1.0, 9/17: 2.0, 9/28: 2.0, 10/12: 1
7/27/17: started Xelox (Capox) cycles
10/17: CT scan. Multiple Peri and Pelvis mets
11/17: CRS/HIPEC. All nodules removed- low PCI
1/18: CT. 2 lung nodules. next CT on 4/24

User avatar
bitchslapped
Posts: 1483
Joined: Tue Sep 09, 2014 3:23 pm
Location: PNW/USA

Re: Lung mets after HIPEC

Postby bitchslapped » Fri Jun 29, 2018 11:14 pm

My friend is coming along ok, AJ. Thx for asking. What is this interesting targeted therapy you're on?

BS
DSS,35YO,unresect mCRC DX 7/'14,lvr,LN,peri,rib
FOLFOX+Avstn 4 Rnds d/c 10/'14
Stent 9/'14
FOLFIRI+Avstn 10/'14
Gone From My Sight 2/20/15
Me:garden variety polyps + precancerous polyp
Carergver x2 DH,DM dbl occupancy,'03-'10
DH dx 47YO mCRC,'04-'07 fried x HAI
DM dx CC 85YO,CC,CHF,stroke,dementia,aphasia

rp1954
Posts: 1379
Joined: Mon Jun 13, 2011 1:13 am

Re: Lung mets after HIPEC

Postby rp1954 » Sat Jun 30, 2018 3:03 am

Even if lung mets are less marker reactive, I would measure and talk about CA199 and LDH at least once, Various highs and lows are useful too.

We had three 6mm lung thingies to deal with at dx.
After a year of varied immunochemo combinations, an oral 5FU prodrug with supplements, cimetidine, high vitamin D3, IV vitamin C and vitamin K2, and later various beta glucans including PSK and WGP:
one lung thingy disappeared, one turned to stone (wife had a period of upper limit calcium levels ~10.x), one thingy just sits there. Some of her success is due to matching or watching the extra markers and blood tests to continuously attack the cancer.

After several years, celecoxib became a necessary component, too.
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC


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