non-specific inflammation...what could it be?

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CLD
Posts: 206
Joined: Fri Mar 27, 2015 7:16 pm

non-specific inflammation...what could it be?

Postby CLD » Fri Apr 06, 2018 11:59 am

A week ago my husband had his 3rd post cancer colonoscopy. He has them yearly because they keep finding polyps. This year, the dr removed 2 polyps (1 was precancerous) and an "area of erosion" in the ascending colon was biopsied. Well we received the report today and the area of erosion is labeled "non-specific inflammation." Does anyone know if this means diseases like Chrones and Ulcerative colitis were ruled out? The dr told me he felt the 1.5 mm area of erosion was to due his asprin therapy. DH also takes prescription 800mg motrin for pain from an accident he had years ago. I plan to ask the dr if he should continue taking the asprin and NSAIDS (with his history) if they are causing distress in his colon. Is there anything else I should be asking? I'm guessing its not too serious since the office didn't call, but we are trying to be proactive. Thanks in advance for your responses!
Wife to DH/ Father of 6 (age 42 at dx) diagnosed Jan 2015 stage IIIC
Tumor deposit in mesentery 13/24 lymph nodes +
CEA at dx: 5
MSS
Low Grade/Mod. Diff.
FOLFOX 6 months
N.E.D until June 2018
PET Scan 6/18
Biopsy confirms cancer in 3 Paraaortic lymph nodes
Folfiri + Avastin (6tx) and Xeloda during radiation
Cancer all over both lungs dx Jan 2019
FOLFIRI +AVASTIN presently

User avatar
CRguy
Posts: 10474
Joined: Sun Feb 10, 2008 6:00 pm

Re: non-specific inflammation...what could it be?

Postby CRguy » Sat Apr 07, 2018 7:14 pm

Yes be proactive .... be VERY proactive all the time !!!!!!!
Welcome to the forum

ASA ( even 81 mg daily ) can cause issues with other NSAIDs ( ibuprofen = Motrin / Advil ) at the levels hubby is taking them,
SO whoever has him on both should have had a discussion with him about that. Not everyone will be affected BUTT .... hubby has an individual situation and the docs need to deal with HIM as an individual.

"non-specific inflammation " simply may mean they cannot find a direct cause in the submitted samples, didn't have other info / tissues to expand the diagnosis, or didn't think it was relevant to a precancerous issue, didn't have special sample preparations to do specific specialized stains ..... ???
I would NOT assume they ruled out anything else
so my blanket recommendation to everyone on this forum is :
ALWAYS ask more questions and push for answers which make sense to YOU and keep nagging until you get those answers.

MAYBE consider :
1 - ask Docs specifically about Crohn's, ulcerative colitis, Lynch syndrome or other hereditary colon cancer risks wrt recurring polyps
==>> Did you test for that ? What were the results ? Do we need to test for that now with this new information ? What happens if we don't test and this is actually the problem ?

My motto : " You will miss more for NOT looking .. than not knowing. " " If we don't even look ... what do you expect to find ? "

2 - get a pain management specialist on board to get different pain meds for hubby, or different treatments which do not cause GIT problems

Cheers and best wishes
On the Journey
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
17 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far


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