Aqx99 wrote:My oncologist called me today with the results of the CT scan I had last week. Everything else looks good, but my thymus is enlarged. She said that she has seen this before in patients that have had pelvic radiation, because their blood counts don't rebound as quickly. My blood counts have been consistently low since my last chemo. We decided that to be on the safe side, I should go for a PET scan. She is having me come in tomorrow to draw my labs again and I am scheduled for the PET on April 6th. Has anyone else here dealt with the same issue?
Aqx99 wrote:..... but my thymus is enlarged. She said that she has seen this before in patients that have had pelvic radiation, because their blood counts don't rebound as quickly. My blood counts have been consistently low since my last chemo. We decided that to be on the safe side, I should go for a PET scan.
Thymic Hyperplasia
Thymic hyperplasia most often occurs as a rebound phenomenon in patients who have received chemotherapy for treatment of lymphoma or germ cell neoplasms. Diffuse hyperplasia occurs within 2 weeks to 12 months after chemotherapy and may manifest with mediastinal enlargement on radiography or may mimic thymic neoplasia on cross-sectional imaging. On PET-CT, thymic hyperplasia typically exhibits only mild FDG uptake, in contrast to marked uptake by recurrent malignancy. Chemical-shift MRI (in-phase and out-of-phase gradient-echo sequences) may be used successfully to differentiate thymic hyperplasia from thymic neoplasia. FROM : Diane C. Strollo, Melissa L. Rosado-de-Christenson, in Clinical Respiratory Medicine (Fourth Edition), 2012
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