There are a lot of similarities between your treatment and mine and I just finished the fifth cycle. I started out at 4000 mg/day of Xeloda and dropped down to 3,500 mg/day on the fourth cycle. On the Oxaliplating, I was at 100% for two cycles and the second cycle was very hard and we dropped to 75% on the third and 70% on the fourth and skipped the fifth. The first four were during times of very cold weather and it was quite challenging dealing with the cold sensitivity.
I had issues with eyelids freezing or not responding, tingling, etc. A balaclava helped with breathing when outside and I covered my self completely when it was cold outside. Having to drink warm drinks was a challenge. I got an electric kettle to make water quickly but I also bought a pair of 40 oz stainless steel vacuum containers which can keep drinks hot or warm for about twelve hours.
The Oxaliplating symptoms decrease with time in general. They didn't for me after the fourth cycle which is why we skipped it for the fifth cycle.
It can be a challenge figuring out which symptoms are coming from which drug but, for me, I get arthritic feelings from the Xeloda in the form of joint stiffness or pain and the tinglies from the Oxaliplatin. The tinglies dissipate with time and the arthritic feeling increases until the off week.
On cramps, I find that adding electrolytes (calcium, sodium, magnesium and potassium) help a lot. It's usually worst on the infusion day. I find that Zuun tablets (you dissolve them in water) work quite well but you can take individual tablets too. The oncologist added Magnesium to the IV on one of my infusion cycles. I think that the Xeloda can also cause diarrhea which shows up as a lot of watery bag output. It's good to maintain hydration (water + electrolytes) when this happens. It is nice to know that you're in the latter stages of treatment in this long marathon.
6/17: ER rectal bleeding; Colonoscopy
7/17: 3B rectal. T3N1bM0. 5.2 4.5 4.3 cm. Lymphs: 6 x 4 mm, 8 x 6, 5 x 5
7/17-9/17: Xeloda radiation
7/5: CEA 2.7; 8/16: 1.9; 11/30: 0.6; 12/20 1.4; 1/10 1.8; 1/31 2.2; 2/28 2.6; 4/10 2.8; 5/1 2.8; 5/29 3.2; 7/13 4.5; 8/9 2.8, 2/12 1.2
MSS, KRAS G12D
10/17: 2.7 2.2 1.6 cm (-90%). Lymphs: 3 x 3 mm (-62.5%), 4 x 3 (-75%), 5 x 3 (-40%). 5.1 CM from AV
10/17: LAR, Temp Ileostomy, Path Complete Response
CapeOx (8) 12/17-6/18
7/18: Reversal, Port Removal
2/19: Clean CT