Postby rp1954 » Sat Mar 24, 2018 10:14 am
If no one offers you anything else, I'd look into trying to slow the cancer down, stomp some sites, improve immune functions, and hit more of their likely molecular roots. You can look at my previous comments on better bloodwork and milder adjuvants in the archive. Although I'm directly concerned with KRAS, it's hard to avoid both in any given paper and necessarily needs to be teased apart and both compared for best understanding. One of the problems of current oncology for mutant mCRCs is that they don't treat fast growing mutants and stem cells spreading mCRC, every day.
One of the molecular keys is/was probably cimetidine added to daily 5FU (e.g. UFT or Xeloda), based on Matsumoto's and others work. However, this far along with previously treated CRC, 5FU will need more intensifiers for immune improvements (e.g. PSK, megavitamin D3, astragulus, WGP) and molecular attacks (e.g. resveratrol, celecoxib, curcumin, boswellia, quercetin, EGCG, MK4) as of high doses as one can get down safely. High dose IV vitamin C is both an immune modulator and a direct molecular attack. Again, a lot of important hints are in expanded, cumulative blood and tissue work.
Last edited by
rp1954 on Sat Mar 24, 2018 10:28 am, edited 1 time in total.
watchful, active researcher and caregiver for stage IVb/c CC. surgeries 4/10 sigmoid etc & 5/11 para-aortic LN cluster; 8 yrs immuno-Chemo for mCRC; now no chemo
most of 2010 Life Extension recommendations and possibilities + more, some (much) higher, peaking ~2011-12, taper chemo to almost nothing mid 2018, IV C-->2021. Now supplements