rp1954 wrote:If no one offers you anything else, I'd look into trying to slow the cancer down, stomp some sites, improve immune functions, and hit more of their likely molecular roots. You can look at my previous comments on better bloodwork and milder adjuvants in the archive. Although I'm directly concerned with KRAS, it's hard to avoid both in any given paper and necessarily needs to be teased apart and compared for best understanding. One of the problems of current oncology for mutant mCRCs is that they don't treat fast growing mutants and stem cells spreading mCRC, every day.
One of the molecular keys is/was probably cimetidine added to daily 5FU (e.g. UFT or Xeloda), based on Matsumoto's and others work. However, this far along, 5FU will need more intensifiers for immune improvements (e.g. PSK, megavitamin D3, astragulus, WGP) and molecular attacks (e.g. resveratrol, celecoxib, curcumin, boswellia, quercetin, EGCG, MK4) as of high doses as one can get down safely. High dose IV vitamin C is both an immune modulator and a direct molecular attack. Again, a lot of important hints are in the expanded, cumulative bloodwork.
Lele88 wrote:Hey Guys,
Thanks for your responses.
I have an appointment with the onc tomorrow and I also read about extended blood tests. I want to ask for a liquid biopsy to get the braf v600 fraction. I have been told it is important to find out the percentage in the blood (meaning between 0 and 50). In case of a high percentage targeting the braf mutation directly seems to be the way to go.in case of a low percentage the standard therapy Folfoxiri and Avastin might work.
Anyone has experience with this?
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