Robino1 wrote:Or am I doomed to die?
That's exactly what my wife asked the night before we went to the hospital for her second surgery, kind of getting cold feet. That was almost 7 years ago.
HIPEC is only successful in a very small percentage.
I don't think they do a very good job on the monthly monitoring and (immuno)chemo side of follow up tx. I did (or would) replace them in a heartbeat.
So, is it possible to reach long term remission by chemo alone?
Dr Edward Lin showed a bunch of stage IV and recurrent mCRC patients whose median OS went somewhere beyond 94 months while on daily capecitabine and celebrex alone. Still lots of missed opportunities there with other mild ingredient add-ons, especially the KRAS/BRAF mutant related ones.
The issue is to intensify the cancer treatment without corresponding increases in side effects. This is primarily possible for us with selected nutriceuticals, mild drugs, and more frequent, improved bloodwork.
Thinking about chemo for life... my hands are truly not liking that option.
(Some?) IV vitamin C patients appear to do much better with Xeloda side effects, without the tissue breakdowns. Ditto other nutraceuticals. Incidentally, IV vitamin C is an active component in treating KRAS/BRAF mutant cells, the best kill or improvements when combined with (daily) 5FU and other adjuvant nutraceuticals
in high potency doses and
When will they finally get a handle on this???? Hell, there has been no cure for any disease since Polio...I'm truly curious if it is possible to go into LONG term remission through chemo only...
Many good, partial answers have been hitting us in the hands for the last 25 years. Almost no one wants to pay attention and do
much of anything about them, patients included. Many medical industry segments are outright resistant to potential improvements that have negative economic dimensions. The Matsumoto related papers imply that most stage 2 and 3 CRC patients, with substantial BRAF mutant cells present at pathology, were cured, -able after a year of oral 5FU chemo and cimetidine, starting two weeks after initial surgery. No RC radiation either, but better surgery. Several Japanese papers showed cimetidine + 5FU helped unresected stage IV patients somewhat for several kinds of GI cancers beyond 5FU alone, but they obviously needed better+more treatment modes and ingredients. We found, targeted and added some of these other ingredients, added an extra surgery, and used better, more biologically logical "treatment rules".