Definitely get extra, outside, independent opinions. I talked to several MDs that use different alternative, less known chemistries with interesting medical literature, too.
We never agreed to oxi-. We have added a lot of things to oral chemo to improve cancer inhibition. Some of it is driven by extra bloodwork, a lot can be done on others' broad recommendations and experience, like Life Extension's or the better integrative doctors.
We've done other things without the oxi- for over 7 years despite sets of real mets, without raising any neuropathies. My wife is still a piano player. There are other chemistries that improve the odds, the big questions are what options exist, who gets to do the targeting, and who gets to give their blessing to it.
Oxi- for adjuvant treatment only adds a small percentage to survival stats. Frankly I think that it is possible to do better than oxi-, targeting some bad CRC types adding cimetidine and/or celecoxib (Celebrex), maybe metformin. Ditto PSK and vitamin D3, based on bloodwork.
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC