The Colon Club

Stanford University just announced that they are developing a cancer vaccine. A clinical trial with 15 patients will start soon.

We know there is no FDA approved cancer vaccine yet for treatment. The lead researcher Dr Levy states the vaccine contains two components activating the T-cells in the tumors. The mice study shows that if the vaccine is injected into one tumor, not only will the affected tumor shrink and disappear, but also the other tumors of the same type in the different locations will disappear as well.

https://med.stanford.edu/news/all-news/ ... -mice.html
http://www.dailymail.co.uk/health/artic ... ccine.html

We understand in the past many potential cancer vaccines failed all to show effectiveness. We hope this 2nd generation of Cancer Vaccine will succeed. If it does succeed, It will be definitely a true and big break-though.

I was coming here to post on this. It is very exciting. I really hope it works. Having such a treatment would bring hope and change so many lives.

Was only reading this this morning,
Looks very promising
Any idea when the results will b published or know anyone doing the trial????
Adele

Thanks for posting, boswind!

From Dr. Levy's mouth to God's ears! This is a promising development!

Seems so promising! Anyone here have any more information? Nice that their universal group of cancers specifically mentions CRC—-so often not the case.

Here is a link to the paper recently published in Science Translational Medicine:

http://stm.sciencemag.org/content/10/426/eaan4488

The abstract is available to read by the public. Subscription required to read the full Text. This is quite amazing result but be aware its still going to be a while before human trials. This is a study in Mice only right now. It requires the tumor to be injected. This is similar to the effect that is shown by injection of Rose Bengal (in a formulation called PV-10 they have been having success with in Melanoma).

Also have a look at the SD-101 and DV-281 drugs by Dynavax which also work on TLR9:

http://www.dynavax.com/our-pipeline/can ... notherapy/

Lots of interesting ways to pump up the immune system to fight cancer. Coming up with a universal one that can be effective at advanced stages of disease will be the real test!

Regards,

GrouseMan

Thank you very much Grouseman! I honestly hoped after I saw the post that you would chime in. I appreciate all your posts and willing to share. Thank you again.

Thanks - I pop in from time to time still now after the passing of my wife back in Jun of last year. I don't comment much unless I have something to contribute. Mostly support of Maia and Tom (DK) but now that Tom is gone there seems to be less of that sort of scientific exchange going on, and I don't have as much desire for researching things as I did when motivated by my wife's condition. I've little time to dig very deep now that I am responsible for everything in our household myself. Work, dogs (8), horse, pigeons (18), house yard etc. I broke 5 ribs back the beginning of November in a fall off my wife's horse, (Trying to keep him fit) which slowed me down for a while. It was the weekend of what would have been our 35th anniversary.

Take care and good luck.

GrouseMan

Thanks for the papers - I'll have a look and ask my son to have a look. It's too late for me but it's always good to know about this stuff for recurrences.

GrouseMan wrote:Thanks - I pop in from time to time still now after the passing of my wife back in Jun of last year. I don't comment much unless I have something to contribute. Mostly support of Maia and Tom (DK) but now that Tom is gone there seems to be less of that sort of scientific exchange going on, and I don't have as much desire for researching things as I did when motivated by my wife's condition. I've little time to dig very deep now that I am responsible for everything in our household myself. Work, dogs (8), horse, pigeons (18), house yard etc. I broke 5 ribs back the beginning of November in a fall off my wife's horse, (Trying to keep him fit) which slowed me down for a while. It was the weekend of what would have been our 35th anniversary.

Take care and good luck.

GrouseMan

(((GrouseMan)))

Thinking of you. 5 ribs, so sorry, that must have been awful "painful". Hope you are doing tons better.

Yes we lost a few good people this past year, your wife, Brownbagger, Tom and BeansMama, just to name a few. I pray for the day, there is a cure for this horrible disease.

Take care of yourself,

Lee

GrouseMan wrote:Thanks - I pop in from time to time still now after the passing of my wife back in Jun of last year. I don't comment much unless I have something to contribute. Mostly support of Maia and Tom (DK) but now that Tom is gone there seems to be less of that sort of scientific exchange going on, and I don't have as much desire for researching things as I did when motivated by my wife's condition. I've little time to dig very deep now that I am responsible for everything in our household myself. Work, dogs (8), horse, pigeons (18), house yard etc. I broke 5 ribs back the beginning of November in a fall off my wife's horse, (Trying to keep him fit) which slowed me down for a while. It was the weekend of what would have been our 35th anniversary.

Take care and good luck.

GrouseMan

You have your hands full. Be careful. You are needed here, especially with Tom gone Thank you again for all the info.

Here is a follow up discussion of this potential Universal vaccine Idea from The Pipeline from another fellow drug discovery chemist you may all be interested in.

http://blogs.sciencemag.org/pipeline/ar ... y-frontier

Enjoy,

GrouseMan.