KathyLynn wrote:...Should I go for chemo/Rad? What does radiation do after surgery? Is it that bad? ...
According to the NCCN Guidelines for Rectal Cancer, if radiation is used, it is to be aimed at the pelvic cavity according to the following specifications:
Radiation therapy fields should include the tumor or tumor bed, with a 2–5 cm margin, the presacral nodes, and the internal iliac nodes...
In your case, the tumor bed would be where your anastomosis junction is now located and it would include the part of the sigmoid colon that was brought down to the rectal stump to form your neo-rectum. The new neo-rectum would have its own set of lymph nodes which were originally located in the sigmoid colon area but have now been moved down into the pelvic cavity. So, these lymph nodes as well as the presacral and iliac lymph node areas would all be irradiated. If there were any ITCs in these lymph node areas, they would likely all be destroyed.
The radiation would have to be accompanied by low dose 5FU-equivalent chemo, and this regimen would be followed for about 5 weeks. In contrast to the radiation segment, the low-dose chemo would circulate throughout the entire body.
Then after these 5 weeks of chemo/rad are finished they may want to continue with about 4 months of regular full-dose chemo to make up the 6 months total of adjuvant therapy recommended for all Stage III cases.
You would have to verify the details of all of this with your oncologists. (This is only a suggestion of what might be in store for you. If you indeed decide to opt for adjuvant therapy, then the doctors will likely follow whatever the standard is in your hospital.)