Signet ring stage , Adenocarcinoma

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Aishwarya
Posts: 1
Joined: Sat Jan 13, 2018 3:33 am

Signet ring stage , Adenocarcinoma

Postby Aishwarya » Sat Jan 13, 2018 3:38 am

Hi evryone.. I need a help.. HOpe u'll help me..PLease its an emergency
MY GRandmother is 62 years old n we got confirmed that she is in 4th stage i.e., signet ring stage of adenocarcinoma..She had undergone appendicitis recently as she was misdiagnosed it as appendicitis.. I wanted to know whether it is curable at this stage by chemotherapy.. n how long can she survive happily.. People pls do respond

Lee
Posts: 5602
Joined: Sun Apr 16, 2006 4:09 pm

Re: Signet ring stage , Adenocarcinoma

Postby Lee » Sun Jan 14, 2018 6:47 pm

Hi and welcome, sorry for the reason you are here.

Yes there are many stage IV folks who are beating this cancer today. Usually surgery is the best course for beating it. Where are her mets? What is her overall health? Has she seen an Onc yet? Is there a plan of action yet?

Sorry butt we need a bit more information to answer your questions betters.

Are you in the USA? Since she is dealing with a stage IV diagnoses, she should really get second opinion at major cancer hospitals or major cancer treatment centers.

Good luck,

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 10 years and counting!

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Robino1
Posts: 461
Joined: Fri Aug 11, 2017 12:09 pm
Facebook Username: Robin.lawthers
Location: Florida

Re: Signet ring stage , Adenocarcinoma

Postby Robino1 » Sun Jan 14, 2018 8:32 pm

I'm stage IV and it is inoperable at this point. I'm really hoping that chemo can get rid of all the cancer.

I hope someone does come along that can give more insight.

Sorry that you had to find us.
At 54 2014 1st colonoscopy colon cancer detect
Colon resect margins clear. No chemo Stage II
2017
Distend abd, pain in intestines.
CT scan seeding & Ascites
Lap diag - cancer on the omentum
CEA 217; 219
FOLFOX started 6/17
CEA 202
8/29/17 CT melting of tumor.
Latest CT scan shows 2 new tumors and return of ascites.
CEA: (2017)9/30 -109; 10/12 -99.1; 11/4 -90.7; 11/30 -70.7; 12/14 -83.4; (2018)1/4 -73.3; 2/1-84.2; 89.2; 89.8; 88.5; 81.8: 93.5; 107; 119
BRAF V600e

Lee
Posts: 5602
Joined: Sun Apr 16, 2006 4:09 pm

Re: Signet ring stage , Adenocarcinoma

Postby Lee » Sun Jan 14, 2018 9:05 pm

Robino1 wrote:I'm stage IV and it is inoperable at this point. I'm really hoping that chemo can get rid of all the cancer. .

Sorry that you had to find us.


My understanding, chemo is a way to get to surgery, Sloan Kettering Memorial has put many people who were told surgery was off the table, to NEDville. Have you looked at 2nd opinions?

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 10 years and counting!

User avatar
Robino1
Posts: 461
Joined: Fri Aug 11, 2017 12:09 pm
Facebook Username: Robin.lawthers
Location: Florida

Re: Signet ring stage , Adenocarcinoma

Postby Robino1 » Sun Jan 14, 2018 9:09 pm

Lee wrote:
My understanding, chemo is a way to get to surgery, Sloan Kettering Memorial has put many people who were told surgery was off the table, to NEDville. Have you looked at 2nd opinions?

Lee


HIPEC would be my only option. I'm not sold on it. I have gotten a second opinion from a #7 rated colon cancer hospital and am keeping them in the loop as far as how my current treatment is going. The seeding on my omentum is/was quite a Lot. That is the only place the metastasis is.

If things change...

¯\_(ツ)_/¯
At 54 2014 1st colonoscopy colon cancer detect
Colon resect margins clear. No chemo Stage II
2017
Distend abd, pain in intestines.
CT scan seeding & Ascites
Lap diag - cancer on the omentum
CEA 217; 219
FOLFOX started 6/17
CEA 202
8/29/17 CT melting of tumor.
Latest CT scan shows 2 new tumors and return of ascites.
CEA: (2017)9/30 -109; 10/12 -99.1; 11/4 -90.7; 11/30 -70.7; 12/14 -83.4; (2018)1/4 -73.3; 2/1-84.2; 89.2; 89.8; 88.5; 81.8: 93.5; 107; 119
BRAF V600e

Lee
Posts: 5602
Joined: Sun Apr 16, 2006 4:09 pm

Re: Signet ring stage , Adenocarcinoma

Postby Lee » Sun Jan 14, 2018 9:19 pm

Robino1 wrote:HIPEC would be my only option. I'm not sold on it. I have gotten a second opinion from a #7 rated colon cancer hospital and am keeping them in the loop as far as how my current treatment is going. The seeding on my omentum is/was quite a Lot. That is the only place the metastasis is.

If things change...

¯\_(ツ)_/¯


Okay, Now I understand, seeding in the omentum is a challenge. Butt know that some people have reached NED with the HIPEC procedure. Skifletcher is just one example. He checks in every few years. Have your looked in something like Keytruda?

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 10 years and counting!

User avatar
Robino1
Posts: 461
Joined: Fri Aug 11, 2017 12:09 pm
Facebook Username: Robin.lawthers
Location: Florida

Re: Signet ring stage , Adenocarcinoma

Postby Robino1 » Sun Jan 14, 2018 11:02 pm

IF I need something other than what is working as of now, I will certainly be looking at any and all options. :)
At 54 2014 1st colonoscopy colon cancer detect
Colon resect margins clear. No chemo Stage II
2017
Distend abd, pain in intestines.
CT scan seeding & Ascites
Lap diag - cancer on the omentum
CEA 217; 219
FOLFOX started 6/17
CEA 202
8/29/17 CT melting of tumor.
Latest CT scan shows 2 new tumors and return of ascites.
CEA: (2017)9/30 -109; 10/12 -99.1; 11/4 -90.7; 11/30 -70.7; 12/14 -83.4; (2018)1/4 -73.3; 2/1-84.2; 89.2; 89.8; 88.5; 81.8: 93.5; 107; 119
BRAF V600e

fumaros
Posts: 231
Joined: Sat Jul 02, 2016 10:26 pm
Location: Syracuse, NY
Contact:

Re: Signet ring stage , Adenocarcinoma

Postby fumaros » Mon Jan 15, 2018 10:25 am

Aishwarya wrote:MY GRandmother is 62 years old n we got confirmed that she is in 4th stage i.e., signet ring stage of adenocarcinoma..She had undergone appendicitis recently as she was misdiagnosed it as appendicitis.


As long as there is life, there is hope. And there are advancements in medicine. However you should get clarification from you grandmother's physicians as signet ring cell (SRC) is a type of cancer histology and doesn't necessarily mean stage IV. Unless you are saying is both stage IV and has a signet ring cell type. SRC is very aggressive, but it also is known to respond well to chemotherapy. It creates a mucin that helps it spread. I researched somewhere that bromelain from pineapples is good at breaking down proteins.
I wish your grandmother and you well, and will be praying.
Diagnosed 4/8/16, age 29
Colectomy 4/20/16
Stage III, T4bN1 Tumor 7x6.5x2. Muscinous Adenocarcinoma with SRC features
2/16 lymph nodes
CEA 4/14/16 - 16.8
CEA 6/2/16 - 1.9
CEA 6/17/16 - 0.87, 7/16 - 1.33, 12/16 - 1.14, 4/17 - 0.6, 7/17 - 0.5, 10/17 - 0.9
FOLFOX began 6/24/16 - 11/25/16
10 round FOLFOX, 2 round 5-FU & Leucovorin
MRI & CT 8/16 - NED, CT 12/16 - 10/17 - NED


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