My tumors were so necrotic that it was impossible to find cells for genetic evaluation. The percentage of dead cancer cells matters. It is a good thing that the pathologists were not able to find living cells with undamaged DNA for analysis.
I did not have biopsy. However my surgeon removed one tumor after 4 treatments for testing and evaluation and it was almost completely necrotic. No cells to perform valuable tests. With more chemo I achieved complete response and I have been clear since May 2016. One more all clear news last week.
My tumors were fast growing ones so the largest had necrosis in the middle of the tumor at diagnosis. Sometimes fast growing mean also fast dying in cancer world. It seemed to be my cancer case. I cannot know what the future will bring but I live my good life right now.
I experienced both situations , you described. And yes, my first oncologists and radiologists were very unhappy seeing the initial necrosis in the middle of the largest 7.5cm tumor.
The situation changed 2 months later when my oncologist came with good news that my cancer was dead and my prognosis changed to good.
Your mom seems to have very good response to chemo.
I would push for surgery right now. There is only a narrow time window for surgery. Tumors usually gain resistance to chemo.
I don't regret my choice of HAI. It worked for me well. I gained a fantastic doctor with amazing team of surgeons. The whole office cheered when they saw another set of good scans. My nurse run to give me a hug
My doctor was very, very close and all smiles.
With fast growing tumors I needed to act fast.
mom of 8 years old twins, dx @ 40 with upper rectal cancer, 10+ liver mets in 6/2015, CEA 140
chemo: 8/2015 - 10/2016 - 4xFOLFIRINOX, 2xFOLFOX, 8xFOLFIRI, 10x5FU, HAI pump -12xFUDR
4 surgeries, complete pathological response
CEA<2 since 10/2015
NED since May 2016
I praise God for every day with my family!