Aqx99 wrote:....a load of crap...Cancer cells and your regular cells feed the same way. There is nothing you can do to specifically starve cancer cells only.
PET scans show IV vitamin C patients quench the radioactive intensity of their Kras/Braf mutant cancer sites, where dehydroascorbate is competitively transported with glucose
and FDG (F18 radiotracer on deoxyglucose for PET). The Ras/Raf mutant cells are metabolically different; these cancer cells have more glucose transporters in the membrane AND have different redox/removal results. Related to the sugar questions, some kind(s) of high vitamin C level is retained for weeks or months in cancer cells, presumably interfering with glucose metabolism also. Also sugar spikes IGF-1.
One of the great fubars of cancer science concerns the unanswered/unasked question of which
vitamin C is best under-what-conditions-when, or which kinds were actually used in any given test. The best animal experimental papers I've seen used intraperitoneal cobalt dehydroascorbate
(or nearby metabolites), 25-40 yrs ago. The treated mice had lived 4x longer at sacrifice, final maximum OS unknown. No follow up since the academic researcher retired, another too-cheap-to-sponsor-cancer orphan. At this point my IV C treated wife is near the 4x dx OS point with less cobalt (oral "mega" B12) but with other necessary stuff too.
If anything, it would make getting treatment harder on the patient because they would not have the strength to fight the effects of the chemo. Also, it is best to have something on your stomach during an infusion because it helps prevent nausea.
The nausea and long term hollowing out are legit discussions, likely solvable several ways. The scientific "sugar" questions are often poisoned by various assumptions and oversimplifications, like "nothing", "feed" or "starve", in the midst of undone and unread science.
Bschreibs wrote: I've recently read some interesting information about the benefits of fasting the day before/day of/day after chemo. The thought is fasting will starve the cancer cells... Has anyone tried this or heard about the benefits from doing so?
We apply continuous, oral 5FU with mild adjunct drugs and nutraceuticals. We used general carb restriction for the first 18-24 months, calorically balanced with healthier fats/oils during the most challenging and successful years around two surgeries. She looked and felt great, even while carrying an "inoperable" LN cluster and other chemo reactive, unbiopsied masses in lungs (6mm thangs) and liver.