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Cancer ‘vaccine’ eliminates tumors in mice

Posted: Thu Feb 01, 2018 10:32 am
by jp81
Activating T cells in tumors eliminated even distant metastases in mice, Stanford researchers found. Lymphoma patients are being recruited to test the technique in a clinical trial.

Injecting minute amounts of two immune-stimulating agents directly into solid tumors in mice can eliminate all traces of cancer in the animals, including distant, untreated metastases, according to a study by researchers at the Stanford University School of Medicine.
The approach works for many different types of cancers, including those that arise spontaneously, the study found.

https://med.stanford.edu/news/all-news/ ... -mice.html

I just hope this becomes available for colorectal trials soon (across the world).

MSI Status Shows No Effect on Metastatic Colorectal Cancer Prognosis

Posted: Fri Feb 02, 2018 10:33 pm
by O Stoma Mia
MSI Status Shows No Effect on Metastatic Colorectal Cancer Prognosis
https://www.curetoday.com/articles/msi-status-shows-no-effect-on-metastatic-colorectal-cancer-prognosis
...Although no associations were found in this study, the possibilities of evaluating genetic biomarkers in CRC are endless. “The final message would be that these efforts of understanding the impact of genetic tumor signatures in patient outcomes definitively has a future,” Aucejo said. “Patients need to understand that that is what they should expect to see moving forward – that the oncologists and surgeons will look more and more in to genetic biomarkers in tumors.”


Other topics discussed st the Symposium:
https://meetinglibrary.asco.org/browse-meetings/2018%20Gastrointestinal%20Cancers%20Symposium

Bacteria play critical role in driving colon cancers

Posted: Sun Feb 04, 2018 11:44 pm
by MonaL
Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer...

...Using a mouse model of colon cancer, the researchers found that animals whose colons were colonized with just one of these species developed few or no tumors. However, when their colons were colonized with both species simultaneously, they developed many tumors, suggesting a synergy between the two types of bacteria.

https://www.eurekalert.org/pub_releases ... 013118.php

Ultra-processed foods 'linked to cancer'

Posted: Fri Feb 16, 2018 2:19 am
by O Stoma Mia
Ultra-processed foods 'linked to cancer'
http://www.bbc.com/news/health-43064290
...The researchers concluded: "These results suggest that the rapidly increasing consumption of ultra-processed foods may drive an increasing burden of cancer in the next decades."
But they said the findings need to "be confirmed by other large-scale" studies and research was needed to establish what could be behind the link.
...
Prof Linda Bauld, Cancer Research UK's prevention expert, said: "It's already known that eating a lot of these foods can lead to weight gain, and being overweight or obese can also increase your risk of cancer, so it's hard to disentangle the effects of diet and weight."

CRC caregiver to be featured in national campaign

Posted: Mon Feb 19, 2018 6:40 am
by O Stoma Mia
http://www.herald-dispatch.com/features_entertainment/ona-resident-featured-in-national-campaign/article_e7d06066-85b1-5076-b8c4-a9e30017947a.html
West Virginia resident Kellie Hoffman is one of 25 people featured in a new public service announcement playing in Times Square in March for Colorectal Cancer Awareness Month, according to a news release from Fight Colorectal Cancer.

Hoffman was her mother's caregiver for 10 years and has become an ambassador Fight Colorectal Cancer, an advocacy organization focused on colorectal cancer policy and research.

The announcement will launch at 9:30 a.m. Wednesday, Feb. 28, during the NASDAQ Opening Bell Ceremony. Hoffman's story will launch on Fight CRC's Facebook page Friday, Feb. 23.


NB: Kellie Hoffman has already registered as a participant in this year's 2018 Call-on-Congress event:

Image



UPDATE:

Also, a news article about Valarie Schlossar, another 2018 Call-on-Congress participant:

https://www.abcactionnews.com/news/region-tampa/local-woman-battling-stage-iv-colorectal-cancer-gets-national-recognition-for-raising-awareness

Image

Alabama's first colon cancer awareness license plate.

Posted: Fri Feb 23, 2018 1:44 am
by O Stoma Mia
Alabama's Top Youth Volunteers Of 2018 Selected By National Program
https://www.prnewswire.com/news-releases/alabamas-top-youth-volunteers-of-2018-selected-by-national-program-300592789.html

Sydney "Merrill Ann" Culverhouse, 16, of Opp, Ala., a junior at Opp High School, used her experience running a tornado relief T-shirt enterprise to launch another charitable endeavor: designing Alabama's first colon cancer awareness license plate. Inspired by her father's colon cancer diagnosis, Sydney worked with her art teacher to design the tag, then partnered with a colorectal cancer charity to put her plan into action; the tag is projected to raise more than $40,000 by June 2018 to support Alabama families affected by colon cancer.


NOTE: Merrill Ann Culverhouse is already registered as one of the participants in this year's (2018) Call on Congress event March 18-20, 2018.

Image

Ref: https://fightcolorectalcancer.org/blog/meet-one-million-strong-merrill-ann-culverhouse-alabama/

Nitrate in drinking water increases the risk of colorectal cancer, study finds

Posted: Sat Feb 24, 2018 12:59 am
by O Stoma Mia
Nitrate in drinking water increases the risk of colorectal cancer, study finds
https://www.sciencedaily.com/releases/2018/02/180220095019.htm
Nitrate in groundwater and drinking water, which primarily comes from fertilisers used in the agricultural production, has not only been subject to decades of environmental awareness -- it has also been suspected of increasing the risk of cancer. The largest epidemiological study ever carried out in this area now shows that there is a correlation -- also when the amount of nitrate in the drinking water is far below the current drinking water standard.

Re: ***News Stories Thread*** ONGOING 2018

Posted: Sun Feb 25, 2018 11:32 pm
by henry123
100 doctors set up Immuno-Oncological Society to frame treament norms

https://m.timesofindia.com/city/mumbai/ ... 062315.cms

NCCN Cancer treatment guidelines questioned in new study

Posted: Fri Mar 09, 2018 3:04 am
by O Stoma Mia
News article:
Cancer treatment guidelines questioned in new study
https://edition.cnn.com/2018/03/07/health/cancer-treatment-guidelines-study/index.html


From the original journal article:
Conclusion The NCCN frequently recommends beyond the FDA approved indications even for newer, branded drugs. The strength of the evidence cited by the NCCN supporting such recommendations is weak. Our findings raise concern that the NCCN justifies the coverage of costly, toxic cancer drugs based on weak evidence.

Ref: Frequency and level of evidence used in recommendations by the National Comprehensive Cancer Network guidelines beyond approvals of the US Food and Drug Administration: retrospective observational study http://www.bmj.com/content/360/bmj.k668

In the War on Cancer, Truth Becomes a Casualty

Posted: Tue Apr 24, 2018 2:13 am
by JJH
NHMike wrote:Between 2005 and 2015, ad spending by U.S. cancer centers soared from $54 million to $173 million. In 2016 alone, Anderson’s seven rotating TV spots were viewed about a billion times. “The appeals raise the stakes, in essence saying you can be saved provided you make the right choice or doomed if you do not,” Steven Woloshin, a physician and medical communication researcher, wrote in an editorial in the Journal of the American Medical Association.

https://www.wsj.com/articles/in-the-war-on-cancer-truth-becomes-a-casualty-1524261478

It's a Wall Street Journal article this morning on the marketing wars in the cancer business.

Toolkit Aims to Address Barriers in Detection of Early-Onset Colorectal Cancer

Posted: Mon Apr 30, 2018 1:31 am
by O Stoma Mia
Toolkit Aims to Address Barriers in Detection of Early-Onset Colorectal Cancer
https://www.curetoday.com/articles/toolkit-aims-to-address-barriers-in-detection-of-early-onset-colorectal-cancer

A physician-based toolkit may help to address the current barriers the health care industry faces in determining family history to detect early age onset colorectal cancer (CRC), according to a special symposium presentation held in New York City on April 26.

When ER stress is bad for cancer

Posted: Tue May 01, 2018 11:25 pm
by jp81
Dietary restriction, such as caloric restriction, enhances tumor immunosurveillance but can be difficult to implement in patients. Rubio-Patiño et al. (see also the commentary by Green) found that the beneficial effects of dietary restriction on tumor immunosurveillance were mimicked by a diet that limited protein intake.


http://stke.sciencemag.org/content/11/528/eaau0066.full

Re: ***News Stories Thread*** ONGOING 2018

Posted: Sun May 06, 2018 3:38 pm
by Maggie Nell
... cancer survivors are more than twice as likely to have mental health problems compared to adults without cancer. Even after recovering from this horrible disease, their fight for health isn’t over. “Anxiety is a persistent problem long after the cancer has been diagnosed,” said Dr. Alex J. Mitchell to the New York Times.


https://www.nami.org/Blogs/NAMI-Blog/Se ... s-Need-Men

Re: ***News Stories Thread*** ONGOING 2018

Posted: Mon May 07, 2018 2:28 pm
by Maggie Nell
'World-first' call for exercise to be prescribed to all Australian cancer patients

When Nicole Cooper was diagnosed with stage four bowel cancer last year, she started to hit the gym hard.
In between bouts of chemotherapy and surgery, the 33-year-old started to work in lengthy runs and sessions of heavy weights.
[...] The Clinical Oncology Society of Australia (COSA) has prepared the Exercise in Cancer Care paper, which states doctors should
prescribe particular exercise regimes and refer patients to exercise specialists with experience in cancer care.


http://www.abc.net.au/news/2018-05-07/c ... nt/9733882

Young adults with cancer are seemingly invisible

Posted: Thu May 31, 2018 10:36 am
by O Stoma Mia
Young adults with cancer are seemingly invisible
http://thehill.com/opinion/healthcare/389774-young-adults-with-cancer-are-seemingly-invisible#.Ww4cE0w6eik.twitter
...Imagine my shock when I read through the Annual Report to the Nation on the Status of Cancer released last week and found no mention of young adults...