Article: Quadruple Wild-Type Metastatic Colon Cancer

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Location: Ontario, Canada

Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby Steph20021 » Tue Dec 12, 2017 7:30 pm

I found this article interesting so wanted to share: ... static-crc
DX 1/31/14 @ 33- SPS-T4a(invades visceral peri), N2a(6/106 LN), M1a(ovary) (Stage 4a) MSS
2/1/14-subtotal col, lost R ovary, temp ileo
3/14-9/14- folfox; sepsis
11/14-CT/PET: L ovary met, pelvic met, (?)ghost liver met(?)
12/14-folfiri -13 rds kept me stable from 3/15-6/15
8/15-HIPEC, hysterectomy et al, 2nd temp ileo, NED?
09/15- cea 0.9
05/16- recurrence in abdo wall and lymph nodes
Jan/17- pulmonary embolism
Feb/17- 1 wk radiation to abdo wall
Currently stable suce Aug/16- on folfiri

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Re: Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby CRguy » Thu Dec 14, 2017 12:41 pm

Thanks for that link Steph.
The targeted therapies are part of the "one size does NOT fit all " mindset in modern oncology
which I believe will lead to good things, and even BETTER things in the future.

Caregiver x 3
Stage IV A rectal cancer/lung met
11 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

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Location: near DC

Re: Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby mhf1986 » Mon Dec 18, 2017 7:24 pm

I looked up DH"s report and it says "all genes to be wild type" so I"m guessing that means DH is Quad Wild Type. Will file that away for future reference.

Thank you to all who post articles, treatments, and other info!

Caregiver to DH, dx age 50, mets to liver/lungs, MSS, quad wild
10/16: left hemicolectomy w/perm. colostomy, CEA 114
11/16: port in, FOLFOX + Avastin; CEA down to 11 by 4/17
6/17: CEA 15, OX discontinued for now due to neuropathy
11/17: CEA 38, changed to CAPOX+A; CEA down to 29 in 12/17
1/18: CAPOX caused bilirubin of 4.5/bad hfs, back to FOLFOX+A
5/18: growth + ascites; 6.4 bilirubin too high for irinitican, start Vectibex
6/18: biliubin down to 2, ascites mostly gone . :D

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