Article: Quadruple Wild-Type Metastatic Colon Cancer

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Location: Ontario, Canada

Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby Steph20021 » Tue Dec 12, 2017 7:30 pm

I found this article interesting so wanted to share: ... static-crc
DX 1/31/14 @ 33- SPS-T4a(invades visceral peri), N2a(6/106 LN), M1a(ovary) (Stage 4a) MSS; BRAF V600E mutation
2/1/14-subtotal col, lost R ovary, temp ileo
3/14-9/14- folfox; sepsis
11/14-CT/PET: L ovary met, pelvic met, (?)ghost liver met(?)
12/14-folfiri -13 rds kept me stable from 3/15-6/15
8/15-HIPEC, hysterectomy et al, 2nd temp ileo, NED?
09/15- cea 0.9
05/16- recurrence in abdo wall and lymph nodes
Jan/17- pulmonary embolism
Feb/17- 1 wk radiation to abdo wall
Aug/16- on folfiri

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Re: Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby CRguy » Thu Dec 14, 2017 12:41 pm

Thanks for that link Steph.
The targeted therapies are part of the "one size does NOT fit all " mindset in modern oncology
which I believe will lead to good things, and even BETTER things in the future.

Caregiver x 3
Stage IV A rectal cancer/lung met
11 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

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Joined: Sat Mar 11, 2017 8:30 pm
Location: near DC

Re: Article: Quadruple Wild-Type Metastatic Colon Cancer

Postby mhf1986 » Mon Dec 18, 2017 7:24 pm

I looked up DH"s report and it says "all genes to be wild type" so I"m guessing that means DH is Quad Wild Type. Will file that away for future reference.

Thank you to all who post articles, treatments, and other info!

Caregiver to DH, dx @ 50, mets to liver/lungs, MSS, wild
9/16 CEA 114, blockage, left hemi, perm. colostomy
11/16 port in, FOLFOX + Avastin
6/17 CEA 15, 5FU + A only due to neuropathy
11/17 CEA 38, CAPOX + A
1/18 CAPOX = hi bilirubin/bad hfs, back to FOLFOX + A
5/18 growth; Vectibex + 75% Irinotecan
7/18 CEA 23, shrinkage
10/18 CEA 28, growth of 2 liver tumors/shrinkage of few and lung nodes
11/18 Lonsurf, looking at spheres, proton, trials
11/19/18 Peace

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