zephyr wrote:My chemo has been stopped for the next few weeks while my oncologist considers other treatment options. The 5FU is no longer working, based upon growth/density of what are believed to be inoperable lung mets. But here's the strange thing, at least to me. My CEA has not risen ... in fact, it's lower than it's ever been, only 0.9. Has anyone else had that experience and what were your thoughts and results?
Unfortunately, CEA isn't always a good marker. My CEA never rose above normal even though I had a huge tumor growing in my uterus for 2 years. I now have many lung mets and normal CEA.
There are many treatments for lung mets depending on location and size. Right now, my mets are all under 1cc and I'm on a maintenance chemo regiment of 5fu + Erbitux. Many people stay stable on 5FU + Avastin. It would be the combining the 5FU with something else that may make it work for you. Procedures include SBRT radiation, RFA ablation and proton beam radiation. Mets need to be at least 1 to 1.5cc for this procedures according to what I've read.
Please update us when your oncologist comes up with a treatment plan.
MSS, KRAS Wild NRAS Mutated
9/2012 Colon Cancer IIB Lft Colectomy 0 lymph nodes 0 Chemo
10/2013 CT clear
11/15 CEA 2.7 to 4.6
11/15 Spread to uterus. Hysterectomy
2/16 Pelvic radiation 25, brachytherapy 3
4/16 - 6/16 Xeloda
6/16 CT Several lung nodules less than 5 mm.
8/16 CT Nodules still present. Most stable. Some growth
10/16 CT Same ^. Onc recommends no tx
11/16 Transfer to UCSD Moores Cancer Center
12/16 Folfox + Avastin failed
2/17 Folfiri + Erbitux
8/17 5FU+Erbitux No 5FU bolus