Mrs. Z, sending you hugs and prayers. Irinotecan may be an oldie but it's a goodie. Tough drug. Do watch out for the diarrhea and get some prescription strength help if needed.
My bible verse last night (great ap on the Ipad) was Ask and you shall receive, Seek and you shall find. I asked for a cure for us all...now, not next year.
Sending more hugs,
Caregiver to DH, dx @ 50, mets to liver/lungs/lymphs, MSS, quad wild
9/16 CEA 114, partial blockage, left hemi, perm. colostomy
11/16 port in, FOLFOX + Avastin
4/17 CEA 11
6/17 CEA 15, 5FU + A only due to neuropathy
11/17 CEA 38, CAPOX + A
1/18 CAPOX caused hi bilirubin/bad hfs, back to FOLFOX + A
5/18 growth/ascites; change to Vectibex + 75% Irinotecan dose
7/18 CEA 23, shrinkage
10/18 CEA 28, growth, considering Lonsurf & trials