Hello everyone. So my husband's tumor was tested for BRAF, NRAS, and KRAS, and all were negative. I feel that this is positive not only for my kids, but also in terms of my husband's response to treatment. He's considered stage 4 because of 1 rogue lymph node that was away from the primary tumor site. We're super optimistic, but trying not to be naive about our circumstances. Can you give me your thougths regarding the results of the genetic testing, and also let me know if there are other tests that should have been done (or that we should request)?
I remember his doctor at MSK (our first opinion) talking about the results of a "mix-match" test (?), which were also negative.
Thank you everyone!
Husband DX Stage IV CC on May 16, 2017
47 years old
Tumor Location: recto-sigmoid
Tumor type: Adenocarcinoma
Tumor size: 7.4 cm
Tumor grade: G3
TNM code: T3N2M1
Positive lymph nodes: 8 out of 20
Baseline CEA value: .9
Perineural invasion: present
Surgical margins: clear (w/in microns)
Primary surgery type: LAR
Folfox (August 2017-January 2018)
Scope June '18 - CLEAR! - 2 polyps removed
PET Scan 10/17/18: 3 positive lymph nodes
Irinotecan + Vectobix (started in November 2018)