So welcome your thoughts. the new scot trial results are beginning to roll out and though i am no oncologist, appears 3 months or 4 cycles of CAPOX is only .09 % statistically inferior to 6 months or 8 cycles. however, toxicity from 6 months as opposed to 3 months is 3x higher and potentially more debilitating.
i just underwent my 3rd infusion of ox and it was not easy. the nurse had to stop twice as i believe it was going in too fast and was making me flush, with a feeling my heart was drowning. the side effects are different this time as well. not so much first bite or swallowing problems, but my forearms, hands, and now mouth are numb off and on. hiccups are intolerable and nonstop. pins and needles off and on in my toes and fingertips.
while i am not a gambling man, would seem to me a .09% difference in the potential outcome is insignificant, especially considering the current and potentially long term debilitating side effects of extended treatment.
we are all working to beat this disease, but i want to do what is best for me and my family while giving consideration to all of the potential outcomes.
hope everyone had a wonderful thanksgiving! hands are starting to claw up again!
Male 48 yrs.
09/10/2017: Colonoscopy 2.2x2 cm lesion - Invasive Adenocarcinoma - NOT Genetic
09/13/2017: CT - No Mets - Very slightly enlarged LN
09/19/2017: Chest Xray, CBC, CEA 2.0. normal
09/20/2017: LAP Rectosigmoid - 8' and 25 LNs removed
09/21/2017: Biopsy - 1/25 LN slight molecular invasion
Dx: Stage IIIa - T3 N1 MX
Chemo of 8 cycles Oxaliplatain with 2 weeks of Xeloda (3 week cycle) for 6 months
10/09/2017: PET negative; no molecular activity, no metabolic activity, NED. T3 N1a M0