My husband's Invitae Common Hereditary Cancers Panel came back with all normal/negative results except for the following --
Variant: c.2593C>t (p.Pro865Ser)
Variant classification: uncertain significance
It looks like there are conflicting classifications of this variant depending on the lab that does the testing:
I really could not understand what the geneticist was talking about when she explained what a variant classification of uncertain significance means. I was able to understand a little more by reading https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544753/
However, I'm at a 3rd grade level when it comes to anything dealing with genetics. Does anyone have a simple explanation of what this finding means?
Thanks in advance!