mpbser wrote:I've been following your thread and I find the difference in the treatment protocol you are on compared to my husband's very interesting. You have a 3B diagnosis and are doing, what, 12 rounds of CAPEOX?
My husband was/is 4A but he only was on 4 cycles of CAPEOX total. His oncologist said that there are two schools of thought on this. One is more conservative about chemo, so to speak, and the other camp is the opposite. I was (still am) not the biggest fan of chemo (to say the least) but I sometimes wonder if my husband was on it enough, especially because he has not stuck to a healthy diet. My husband does not seem worried, however.
My program is 8 rounds of CAPOX. The 12 rounds is for Folfox. They work out to the same period of time - 24 weeks. The CAPOX is 3-week cycles, the FOLFOX is 2-week cycles. My DFCI Oncologist said 4 minimum, 8 maximum, 6 is the sweetspot. I've seen people all over the place on the number of cycles, the reductions or elimination of Oxyliplatin, etc. The experimentation is feeding big data and the data is changing or getting more accurate with more and more people and the records of what they are getting.
The course of chemo is very hard and you do feel like getting it over with as soon as possible and also having to deal with permanent side-effects. We don't necessarily know if there are side effects down the road on the newer drugs. A co-worker had breast cancer decades ago and has developed MS recently - it's a known side-effect of the chemo drug that she took but it took a long time to affect her. So sometimes is a trade-off in intensity. I have seen people in Stage 4 that turned out better than Stage 3 - I think that there are a ton of variables out there on staging, chemo, and ultimate results.
I haven't seen your posts in a while (though I don't spend as much time here as I used to due to work). How are you both doing?