In his Blog post DK37 wrote:
"Q. Many CRC patients have low CEA measurements in their blood tests, can RO6958688 work in those patients? ...
A. There is not a direct correlation between the amount of CEA expressed by a patient’s tumors and CEA in that patient’s bloodstream (ref. https://www.ncbi.nlm.nih.gov/m/pubmed/9378556/ )
– so yes, the drug should be able to work even if a patient has low blood CEA levels. Oftentimes a tumor expresses a lot of CEA – it just isn’t released into the blood allowing it to be measured by the standard CEA blood test!"
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