Dan, IF you're not sure about doing chemo, one alternative would be doing an immunotherapy trial with a vaccine to prevent recurrence Immunotherapy trial for those NED
A fellow on this board, Maellous
, went recently for it, because he had a DPD deficiency --a problem to metabolize 5-FU, so chemo was not possible.
Someone who explored (is exploring) other alternative is Sophy, who underwent a very extensive resection of lung mets years ago and is doing Xeloda --at LOW dose-- plus a NSAID --ADAPT protocol, a total oral regimen-- during the almost 3 last years, as a measure to prevent recurrence viewtopic.php?f=1&t=57644&p=454418
The ADAPT aims to target the stem cancer cells, not the rapidly dividing cells. Otherwise, as PainInTheAss said, doing chemotherapy at the MTD --maximum tolerated doses--, without visible cancer, doesn't really make many sense --for certain literature. Low dose chemo acts more as immunomodulation than as cytotoxic.
I'm going to second Maia's recommendations here. I like both of these options. Even if you do nothing else, I'm thinking celecoxib might be helpful.
11/14 Dx sigmoid CC @ 45yo
12/14 Colectomy + hysterectomy
Stage IIIB, T3N1bM0, 2/20 nodes, MSS, G2, KRAS(A146T), TP53, SMAD4, ERBB2, CEA 1.0
2/15-7/15 XELOX, Celebrex & many supplements
3/16 Ovarian mass removed. Benign fibroid
9/16 clean colonoscopy
4/18 clean CT
Ongoing Celebrex, cimetidine & other carefully-targeted supplements
Post-chemo CEA 3.0, 2.5, 2.3, 2.0, 1.6, 1.3, 1.8, 2.1, 1.8, 2.0, 1.8, 1.9, 1.7, 1.5, 1.6, 1.5, 1.4, 1.4, 1.3, 1.3, 1.6, 1.6, 1.3, 1.4
Mom to a 4 & 6yo