My own SitRep would be :
May 2007 - colonoscopy / biopsy confirms rectosigmoid adenocarcinoma, CT, MRI, many blood tests follow
June 2007 - 6 weeks neo-adjuvant chemoradiation with Xeloda ( 3600 mg/day ), blood tests, CTs
August 2007 - TME via LAR of primary tumour, originally Stage IIIC, temp ileostomy,
pCR ( pathological complete response to chemo-rad )
So if you are asking if neo-adjuvant chemoradiation works to accomplish a positive outcome ...?
Answer = Yes it can .. BUTT each situation is different.
Now please note I had pCR not cCR ( had the surgery and was confirmed by pathology review of the actual tumor site )
cCR is a clinical impression after treatment, without the full pathology being known ... BUTT a lotta scans and blood tests done to get a comfort zone about the results. The big discussion being : does a patient with cCR then also have surgery ?
I did and still had a recurrence 3 years later which was picked up by active aggressive monitoring.
Welcome to the forum
All the best to MOM and her new challenges.
Keep us in the loop and hopefully we can give you some feedback which will help you both