TAPUR

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HopeForJesse
Posts: 249
Joined: Wed Feb 24, 2016 9:39 am
Location: Philadelphia

TAPUR

Postby HopeForJesse » Sun Jun 04, 2017 5:57 pm

No charge access to cancer drugs when other lines of treatment are exhausted.

http://www.tapur.org/patients

"ASCO's Targeted Agent and Profiling Utilization Registry (TAPUR) Study is a non-randomized clinical trial that offers patients access to molecularly targeted cancer drugs and collects real-world data on clinical outcomes to help learn the best uses of these drugs outside of indications approved by the FDA. Since its launch last year, TAPUR has continued to grow, with more than 285 participants registered and more than 100 clinical sites participating as of mid-May. For more information, please visit tapur.org or cancer.net/tapur"
DH DX 01/16 49 YO inop RC stage IV liver mets
MSS TP53 APC,BRCA2
12/15 CEA 241, FOLFOX to 11/16
LAR/ileo 5/16 Clear margins 1/29 nodes
HAI, reversal, liver resections7/16
FUDR 8/16 -NED 3 mos
Rising CEA 3/17 Xeloda, 5/17 -12/17 Erbitux & Iri stable but lung/lymph mets CEA 2.7
5/18 5 days SBRT radiation to sternum 10/22/18 surgery to remove zyphoid process met
6/11/19 5FU added to cetuximab and irinotecan CEA 16
Ephesians 3:20 Our God is able to do immeasurably more than we can ask or imagine!

Lee
Posts: 6207
Joined: Sun Apr 16, 2006 4:09 pm

Re: TAPUR

Postby Lee » Mon Jun 05, 2017 4:37 pm

Bump for those who missed this the 1st time.

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 16 years and counting!

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CRguy
Posts: 10474
Joined: Sun Feb 10, 2008 6:00 pm

Re: TAPUR

Postby CRguy » Mon Jun 05, 2017 4:54 pm

Thought I had posted these links ???? :oops:

anyway here is more background and discussion on TAPUR which is very POG like in its strategy and implemetations.

Maurie Markman on the Groundbreaking TAPUR Trial

What is the TAPUR Study?

The TAPUR study by ASCO

About the TAPUR Study

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)

This link requires a free registered login to view in its entirety :
ASCO Expands TAPUR Sites; Inks Collaborations to Investigate Precision Oncology Globally
When the study launched over a year ago, TAPUR was enrolling patients into 35 sites. But in the coming months eight new centers at 36 locations will begin to recruit patients, increasing the number of study sites to more than 100 in 20 US states. These sites will offer patients the chance to enroll in study arms investigating 15 targeted treatment options that seven drug companies have provided.

As part of its strategy to expand recruitment efforts, ASCO lowered the eligibility age from 18 years down to 12 years, so that adolescent patients with advanced cancer could join the study. Additionally, ASCO partnered with the Canadian Cancer Trials Group and the WIN Consortium, which are developing studies based on the TAPUR basket design. ASCO, WIN, and CCTG will share study results to improve understanding of genomically defined treatment strategies.
Caregiver x 4
Stage IV A rectal cancer/lung met
17 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

KElizabeth
Posts: 400
Joined: Sat Oct 31, 2015 12:41 pm
Facebook Username: KElizabeth
Location: Omaha

Re: TAPUR

Postby KElizabeth » Mon Jun 05, 2017 10:19 pm

Following. There's actually an Omaha location. I'm intrigued now.
Female age 39- ,2 teens.
Colon Cancer - DX March 2013
Age 34 at DX - Stage III B
Resection surgery -May 2013
FOLFOX - June, 2013 to Sept, 2013
5FU plus leukavorin Sept, 2013 to Dec, 2013
METs liver and lungs discovered Sept, 2015
KRAS - MSS
FOLFIRI plus Avastin - Sept, 2015 - July 2017
Durvalumab and Cediranib Sept 2017 Dec 17
FOLFOX with desensitization protocol - current


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