mpbser wrote:Absolutely, AT.
We will certainly know more when we get Friday's liver MRI done. We also will need to figure out whether or not the additional tumor(s) that were found this morning in his colon are resectable or not. The findings are pretty bad:
- Two 3 to 7 mm polyps in the cecum. Resected and retrieved.
- One 1.5 cm polyp in proximal ascending colon. Complete resection. Partial retrieval. (That's interesting... a complete resection but partial retrieval. hmmm?)
- Likely malignant, nearly completely obstructing tumor at 55 cm proximal to anus. Biopsied. (We are so surprised that the surgeon could not [did not] feel this when he had the colon in his hands and "squeezed" it to feel for additional malignancies.)
- One 2 cm polyp at 40 cm proximal to anus. Resected and retrieved.
- A thickened fold concerning for malignant infiltration at 25 cm proximal to anus. The lesion took up almost half the circumference of the colon in this area. Biopsied.
-Christine
mpbser wrote:"Xeloda is inferior to Xelox." Please substantiate this claim. As I have stated, many studies linked to on this forum say otherwise.
"Xeloda is inferior to Xelox." Please substantiate
mpbser wrote:At the first appointment, husband asked if there was a non-IV or pump (I don't think I was clear in my earlier posting on this) alternative and she said Xeloda. She gave us the information sheets for Folfox and for Xeloda. Husband asked if she was aware of any side by side research studies comparing the two. She said there was none. [I went home that day and checked to see if this was accurate. It wasn't. Not only inaccurate, but studies have shown Xeloda (oral) is just as effective as 5-FU (IV). This forum has many links to such studies. Thank you!]. She made no statements as to the efficacy and safety of one over the other. The conversation was such that Xeloda would be an acceptable substitute for Folfox.
mpbser wrote:At the second appointment, her recommendation was different although none of the variables had changed. She now said that the preferred treatment, if non-pump, was Xelox and referred to Xeloda as "inferior." She did not say what it was inferior to. We asked for studies to support this claim and have yet to see one.
Xeloda is inferior to Xelox." Please substantiate
Volume 15, No. 13, p1481–1492 wrote:Combination therapy with oxaliplatin provided consistently improved outcomes without adversely affecting post-relapse survival in the adjuvant treatment of stage III colon cancer, irrespective of whether the fluoropyrimidine backbone was capecitabine or leucovorin and fluorouracil. These data add to the existing evidence that oxaliplatin plus capecitabine or leucovorin and fluorouracil is the standard of care for the adjuvant treatment of stage III colon cancer.
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