Hi all,
My DH has been in treatment for stage 4 colorectal with mets to liver and peritoneum. He was diagnosed in Nov 2016 starting treatment right away in Dec. unfortunately due to side effect complications he couldn't tolerate 5-FU and ended up on irinotecan-avastin and raltitrexid. After about 4 doses they did a ct scan and said it's not working due to the cancer may have grown about 1-2 mm. We were to switch to oxaliplatin + raltitrexid. At that time he developed jaundice and ascites (abdominal fluid build up) the docs said his bilirubin is quite high and to now prepare ourselves as he likely will not make it, and his liver can no longer tolerate chemo or trials. They did administer then chemo at 25% as a sort of Hail Mary that it could help his liver last week. He is only 38 and at the beginning was told since his health is so good he'd be idea for trials etc...I'm not sure if the chemo is what killed his liver but we are worried now we are at the end with no options. Has anyone had success with oxaliplatin? Or with liver issues getting better on chemo? We aren't sure if this can turn around or if we should be preparing for the worst as the doctors keep saying they are worried. Thank you all xo