Adjuvant chemo soon or too late?

Please feel free to read, share your thoughts, your stories and connect with others!
mtipte
Posts: 58
Joined: Mon Dec 19, 2016 4:35 pm
Facebook Username: mario tipte
Location: Lima, Peru

Adjuvant chemo soon or too late?

Postby mtipte » Thu Apr 13, 2017 10:04 am

Hey all,

my mum is much better now after some bladder problems and infection. The appointment with the onc was delayed due to this and changes with the staff in the clinic. So her appointment is this Monday. What worries me is adjuvant chemo, I have read some literature that the effects of chemo after surgery when neoadjuvant therapy was applied is controversial. Idk what do you think?. I would also like to know about the standard gap between surgery and adjuvant therapy.

She's used to xeloda with few side effects, hope the doc will suggest only that as she suffers from hypertension. I read here most of you had 5fu and platinum, but also the effects seem to be severe (neuropathy).

Help please.

:)
I'm a caregiver of my mother 60 y/o
dx 09/16 RC III CEA 9
Chemo/rad 28 from 10/16 till 12/16
Xeloda
multiple lymph nodes
Adenocarcinoma low grade invasive

Now 2000 mg Xeloda for 2 weeks as maint. before surg.
24/01/17 CEA 4,9
APR surgery permanent colostomy :( 24/03/17
3/26 nodes involved - clean margins
Staged after surgery: T3N1Mx
Waiting for adyuvant chemo.
Infection due to bladder problems. Slow recovery.

God is faithful. Only Jesus.

jhocno197
Posts: 744
Joined: Mon May 11, 2015 9:33 pm

Re: Adjuvant chemo soon or too late?

Postby jhocno197 » Thu Apr 13, 2017 10:09 pm

I think it is supposed to start within 12 weeks, ideally within 8.
DH - dx Dec 2014, stage IV with bladder & peritoneal involvement - non-resectable
Colostomy
FOLFOX failed
FOLFIRI failed
Tumor actually distending pelvic skin
Not a candidate for last-ditch pelvic exenteration
Stivarga finally begun 2/19/16
Tumor growing/fungating
Lonsurf started 11/18/16
Died 3/10/17

User avatar
ANDRETEXAS
Posts: 527
Joined: Fri Feb 14, 2014 11:01 am
Location: Austin, Texas

Re: Adjuvant chemo soon or too late?

Postby ANDRETEXAS » Fri Apr 14, 2017 12:42 am

My goal was to start chemotherapy within 4 weeks of surgery. Fortunately, everything healed properly, and I was able to do so. I think the general hope is within 8 weeks, but that varies from patient to patient. As in all cases, each patient is different.
2014
2/10 - Colon resect
2/13 - DX- Stg IIIb
3/7 - Port placed
3/11 - FOLFOX (12 rds w/full oxi)
8/14 - Chemo finish
8/25 - CT- Inc
9/5 - clean PET
12/10- clean CT
2015
3/2 - Colonoscopy & port removed
3/4- clean CT
9/21- clean CT
2016
3/23- clean CT
2017
2/22- clean CT

ONE DAY AT A TIME !

PainInTheAss
Posts: 632
Joined: Tue Jul 02, 2013 3:08 am

Re: Adjuvant chemo soon or too late?

Postby PainInTheAss » Sat Apr 15, 2017 1:23 am

I didn't start chemo for about 4 months after surgery because my APR wound wasn't healing. They never said anything to me about that affecting my prognosis, so I never worried about it. If there are any circulating cells, zap them when you can.

As far as the effectiveness of adjuvant chemo, the benefit is on a sliding scale according to (prechemo rad) stage. Yes, there is little benefit for a IIa, but there is a LOT of benefit for a IIIc. I had the same questions and the same reservations and my Onc very patiently pulled out the graphs and charts to show how much it helped in my case. He sold me. I suggest you make an appointment at the end of the day next time and break out your questions. They are a lot less frantic when you are the last patient of the day. It really helps to believe in it to get through it. Chemo sucks.
47yo single mom of 4 (24, 21, 18, 16) at Dx
6/13 - RC T4b IIIc 5LNs on PET CEA 5.4
8/13 - Finish chemorad
10/13 - APR/hyst+ovaries/perm colostomy 2/12 nodes+
6/14 - Finish Xelox 6 rds
1/15 - CT clear CEA 0.2
10/15 - CT/MRI clear CEA 0.7
4/16 - CT clear
10/16 - CT/MRI clear CEA 0.6

mtipte
Posts: 58
Joined: Mon Dec 19, 2016 4:35 pm
Facebook Username: mario tipte
Location: Lima, Peru

Re: Adjuvant chemo soon or too late?

Postby mtipte » Mon Apr 17, 2017 6:22 pm

PainInTheAss wrote:I didn't start chemo for about 4 months after surgery because my APR wound wasn't healing. They never said anything to me about that affecting my prognosis, so I never worried about it. If there are any circulating cells, zap them when you can.

As far as the effectiveness of adjuvant chemo, the benefit is on a sliding scale according to (prechemo rad) stage. Yes, there is little benefit for a IIa, but there is a LOT of benefit for a IIIc. I had the same questions and the same reservations and my Onc very patiently pulled out the graphs and charts to show how much it helped in my case. He sold me. I suggest you make an appointment at the end of the day next time and break out your questions. They are a lot less frantic when you are the last patient of the day. It really helps to believe in it to get through it. Chemo sucks.


Thanks for your answer, it gives me hope. Today she saw the onc and she said the same: up to 8 weeks to start chemo and Xelox for 4 months will be adjuvant chemo for her. I read terrible things about this, believe that it will work indeed helps so just about to start chemo soon and me reading how to cope with xelox effects to help her.

Thanks for all the replies.

:)
I'm a caregiver of my mother 60 y/o
dx 09/16 RC III CEA 9
Chemo/rad 28 from 10/16 till 12/16
Xeloda
multiple lymph nodes
Adenocarcinoma low grade invasive

Now 2000 mg Xeloda for 2 weeks as maint. before surg.
24/01/17 CEA 4,9
APR surgery permanent colostomy :( 24/03/17
3/26 nodes involved - clean margins
Staged after surgery: T3N1Mx
Waiting for adyuvant chemo.
Infection due to bladder problems. Slow recovery.

God is faithful. Only Jesus.

PainInTheAss
Posts: 632
Joined: Tue Jul 02, 2013 3:08 am

Re: Adjuvant chemo soon or too late?

Postby PainInTheAss » Thu Apr 20, 2017 5:17 am

mtipte wrote:
PainInTheAss wrote:I didn't start chemo for about 4 months after surgery because my APR wound wasn't healing. They never said anything to me about that affecting my prognosis, so I never worried about it. If there are any circulating cells, zap them when you can.

As far as the effectiveness of adjuvant chemo, the benefit is on a sliding scale according to (prechemo rad) stage. Yes, there is little benefit for a IIa, but there is a LOT of benefit for a IIIc. I had the same questions and the same reservations and my Onc very patiently pulled out the graphs and charts to show how much it helped in my case. He sold me. I suggest you make an appointment at the end of the day next time and break out your questions. They are a lot less frantic when you are the last patient of the day. It really helps to believe in it to get through it. Chemo sucks.


Thanks for your answer, it gives me hope. Today she saw the onc and she said the same: up to 8 weeks to start chemo and Xelox for 4 months will be adjuvant chemo for her. I read terrible things about this, believe that it will work indeed helps so just about to start chemo soon and me reading how to cope with xelox effects to help her.

Thanks for all the replies.

:)


There are a lot of great tips on this site, but you have to dig for them. A few things that stand out for me, Ativan can help with muscle related symptoms if she has any like leg cramps, blurry vision, muscle freezing, etc. The oxi changes the way food tastes temporarily, kind of like how brushing your teeth changes how orange juice tastes. I only wanted to eat mashed potatoes for two days after my infusion. Tomato based foods and dairy tasted terrible to me. Ketchup was disgusting. Bean burritos from Taco Bell tasted amazing, and I don't normally eat Taco Bell. Because of the cold sensitivity, hot and warm drinks were the best for me. I drank a lot of coffee and warm tea. I felt okay immediately after the infusion, but I would sleep for 24 hours two days after. My teenage daughter would say she lost me to the sleep monster. I never threw up, but I was just very tired. Each infusion made me even more tired so by the last one, I could barely get out of bed. It took a long, long time to recover, too, to somewhat like my old self. Years, actually. It's only worth it because it may have saved my life.
47yo single mom of 4 (24, 21, 18, 16) at Dx
6/13 - RC T4b IIIc 5LNs on PET CEA 5.4
8/13 - Finish chemorad
10/13 - APR/hyst+ovaries/perm colostomy 2/12 nodes+
6/14 - Finish Xelox 6 rds
1/15 - CT clear CEA 0.2
10/15 - CT/MRI clear CEA 0.7
4/16 - CT clear
10/16 - CT/MRI clear CEA 0.6


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: ACPdiddy, mbrasil13 and 41 guests