Don't despair, there are things that you may be able to do. This particular mutation can be found in colon cancer, but is also well know in melanoma. See the following link.https://www.mycancergenome.org/content/ ... ma/braf/54
andhttps://www.mycancergenome.org/content/ ... r/braf/54/
If your oncologist is a forward thinking doctor, and he can talk your insurance into it, they may be able to treat you with a drug that works well with melanoma's, having this same mutation. Perhaps a combination of one of those drugs and maybe a checkpoint inhibitor to make it go from MSS to more MSI like, might do the trick..
DW 53 dx Jun 13
CT mets Liver Spleen lung. IVb CEA~110
Jul13 Sig Resct
8/13 FolFox + Avastin 12Tx mild sfx
Ongoing 5-FU Avastin every 3 wks.
CEA: 9/23/13 53 10/21/13 22 12/2/13 8 1/13/14 3.7 8/12/14 2.3 7/2/15 4.0 8/21/15 5.9
7/7/14 CT Can't see the spleen Mets Stable until... CEA up
8/16/15 CT new abdominal spots. Now Iri, 5-FU, Avastin every other week.
1/16 Iri, Erbitux and likely Avastin (Trial) CEA going >.
1/17 CEA up again dropped from Trial, Mets growth 4-6 mm in abdomen