Hi. Things are good overall I think.
Recent developments. Had a PET scan last week which showed a small area of FDG uptake with no corresponding lesion on CT. They ordered an MRI with liver specific contrast which is supposedly the most sensitive/specific imaging for liver mets and it showed nothing. Onc still considers me to be NED. Thinks that the FDG uptake may be either inflammation/scarring from the SIRT OR pseudoprogression (something about lymphocytes aggregating in certain areas). Plan is to continue Keytruda and monitor closely.
Has anyone else experienced having sudden spots on PET scan while on immunotherapy then having them resolve eventually? Also if anyone could point me to an immuno trial with a site in Asia or advise me on how to source Keytruda at a lower cost it would be much appreciated. At present I am paying for the drug out of pocket and I am worried about long term sustainability. I was hoping that after 1 year my onc would consider discontinuing it or at least dosing at longer intervals. With recent questionable findings though looks like that discussion will have ton wait.[/quote]
I am having my pembro covered through Mercks compassionate care program. I was denied at first but after doing 3 doses on my own and my tumours showing improvement we reapplied and they are now covering my drugs. I hope you find a way to get some aid as the costs accumulate quickly![/quote]
Hi. May I ask where you reside?
Diagnosed St. IV Colon CA @ 37, male, Kras wild type, MSI-high (2014)
11/2014 Right Hemicolectomy + Liver Resection
12/2014 - 6/2015 FOLFOX + Cetuximab
10/2015 - Recurrence liver
Liver resection 10/2015
FOLFIRI 11/2015 - 5/2016
Recurrence liver, nodes 11/2016
Pembrolizumab 12/2016 -> pseudoprogression (?), biliary obstruction -> biliary stenting
Chemo 4x: most mets inactive and smaller on PET-CT
March 2017 - Back on Pembrolizumab
Sept 2017 - SIRT