Curcumin: What Brand and Where Do You Purchase

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testing765
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Curcumin: What Brand and Where Do You Purchase

Postby testing765 » Wed Jan 04, 2017 5:31 pm

Hi. If you choose to use curcumin, I would like to know what brand you use and where do you purchase it? Do you use the type that includes bioperine? Bioperine is derived from black pepper, correct? And what amount of curcumin do you take on a daily basis? Do you just take it with your other vitamins and supplements? Thank you.
male-age 44 at diagnosis
8/14-clnscopy
8/14-CT scan,no mets
9/14-left colectomy,CEA 2.2 before surgery
pT2pN2bpM0
3 cm tumor in dscnding colon
7/23 pos LNs
low grade MSI stable
10/14-start folfox
1/15-CT & PET scan and sigmdoscopy- no mets
3/15-finish folfox
9/15- colonoscopy- 3 polyps removed
10/15- CT scan, NED
10/16- CT scan, NED, CEA 1.6
10/14 1.9; 4/15 2.8; 5/15 2.4; 9/15 2.8; 12/15 3.1; 1/16 3.0; 4/16 2.5; 7/16 2.5; 10/16 1.6; 1/17 1.9

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CRguy
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Re: Curcumin: What Brand and Where Do You Purchase

Postby CRguy » Wed Jan 04, 2017 6:37 pm

http://www.aor.ca/en/product/curcumin-active

click on the RESEARCH tab then the BACKGROUND tab to see their process for absorption / bioavailability for this product.
I took it as anti-inflammatory pain relief for arthritic issues with success.

Generally it is accepted that piperine enhances curcumin absorption. BioPerine® is actually a branded product.
AOR's product uses solid lipid coating to enhance absorption and prolong active blood levels beyond uncoated curcumin.

IMO...... AOR is a legit company with reliable products.

Cheers
CR
Caregiver twice
Stage IV A rectal cancer/lung met
10 Year survivor
my life is an ongoing NONrandomized UNcontrolled experiment with N=1 !
Review of my Journey so far
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rp1954
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Re: Curcumin: What Brand and Where Do You Purchase

Postby rp1954 » Wed Jan 04, 2017 7:04 pm

Consumer Labs, founded by an ex-FDA chemist, reviews supplements in a harsh way for dosage and purity. Those curcumin products tested satisfactorily for the combination and strength that you want can be price shopped. Also Margaret's Corner, a survivor site on multiple myeloma, primarily using high dose curcumin, is extremely interesting.
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC

lpas
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Re: Curcumin: What Brand and Where Do You Purchase

Postby lpas » Wed Jan 04, 2017 10:30 pm

I take C3, which is the blend used in many research studies. It does include BioPerine. Many different companies market C3 under their label. I generally use this one:

https://www.amazon.com/gp/product/B00JA4TLTI/ref=oh_aui_detailpage_o01_s00?ie=UTF8&psc=1

Check out this article for some dosage recommendations. Most NDs seem to recommend 2 to 3 grams per day.

http://www.lifeextension.com/Protocols/Cancer/Colorectal/Page-01
11/14: Dx sigmoid CC @ 45yo
12/14: laparoscopic colectomy + hysterectomy
Stage IIIB, T3N1bM0, 2/20 nodes, MSS, G2, KRAS (A146T), TP53, SMAD4, ERBB2, pre-surgical CEA 1.0
2/15 to 7/15: XELOX, celecoxib & many supplements
3/16: Ovarian mass ID'ed on US, rt ovary removed. Benign fibroid.
9/16: clean colonoscopy
3/17: clean CT
Post-chemo CEA: 3.0, 2.5, 2.3, 2.0, 1.6, 1.3, 1.8, 2.1, 1.8, 2.0, 1.8, 1.9, 1.7, 1.5, 1.6, 1.5, 1.4
Mom to a 3 & 5-year-old

gfpiv
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Re: Curcumin: What Brand and Where Do You Purchase

Postby gfpiv » Wed Jan 04, 2017 10:56 pm

I used to take a BCM-95 curcumin formulation, since I believe I read that it was the formulation that was used in one or more studies on colon cancer effectiveness, with high bioavailability. I personally took one pill per day (not sure the mgs), though who knows what the ideal dose would be. I should probably still be taking it prophylactically, but haven't for a couple years now.
Chip
DX stage IV CC Jan '10, numerous unresectable liver mets
FOLFOX + Avastin Feb-Jul '10
Colon resection, HAI install Aug '10
Systemic FOLFIRI and hepatic FUDR Dec'10-May'12
Chemo break May'12-pres (tumors calcified & stable, knock on wood)
Billiary bypass surgery and SBRT on pesky liver met in 2015

fumaros
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Re: Curcumin: What Brand and Where Do You Purchase

Postby fumaros » Thu Jan 05, 2017 12:13 pm

I use longivida - from (https://www.amazon.com/Curcumin-Longvid ... s=longvida) because there was a doctor who reviewed different turmeric supplements and said this provided the best availability.

To be honest I also have curcumin from brands that use BCM-95, C3, and "curcumin with bioperine" formulations; i cycle through the lot of them during the week, what can i say, i am a little mental and wanted to cover all my bases.
Diagnosed 4/8/16, age 29
Colectomy 4/20/16
Stage III, T4bN1 Tumor 7x6.5x2. Muscinous Adenocarcinoma with SRC features
2/16 lymph nodes
CEA 4/14/16 - 16.8
CEA 6/2/16 - 1.9
CEA 6/17/16 - 0.87, 7/16 - 1.33, 12/16 - 1.14
FOLFOX began 6/24/16 - 11/25/16
10 round FOLFOX, 2 round 5-FU & Leucovorin
CT 8/16 - NED, MRI & CT 12/16 - NED

Teddi
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Re: Curcumin: What Brand and Where Do You Purchase

Postby Teddi » Fri Mar 17, 2017 11:39 pm

I use Curaphen by Euromedica. It has botswelia to increase the bioavailability. Got it on the advice of my ND.

Teddi
47 at diagnosis
Colonoscopy, biopsy, CT, PET 6/14
Rectal cancer (tentatively) Stage III-b, MSS
Xeloda and radiation 25x finished 8/14
FOLFOX 5 cycles
Surgery 1/23/14 ~ T1N0MX ~ temp illeostomy
FOLFOX 3 cycles = total of 8
Illeostomy reversal 4/8/15
Clean scans x2, clear colonoscopy 9/15

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CRguy
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Re: Curcumin: What Brand and Where Do You Purchase

Postby CRguy » Sat Mar 18, 2017 1:22 am

Would you / your ND be able to give a reference for increased bioavailability ?

Boswellia species have their own spectrum of reported anti-inflammatory properties but I have not seen any reference to it increasing bioavailability of other compounds.

Thank you
CRguy
Caregiver twice
Stage IV A rectal cancer/lung met
10 Year survivor
my life is an ongoing NONrandomized UNcontrolled experiment with N=1 !
Review of my Journey so far
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LPL
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Re: Curcumin: What Brand and Where Do You Purchase

Postby LPL » Sat Mar 18, 2017 12:18 pm

Hi testing765
You wrote:
If you choose to use curcumin, I would like to know what brand you use and where do you purchase it? Do you use the type that includes bioperine? Bioperine is derived from black pepper, correct? And what amount of curcumin do you take on a daily basis? Do you just take it with your other vitamins and supplements? Thank you..


I''m a caregiver that has been advised by my health professional to take both Curcumin and Resveratrol.
As I have read that both can be of benefit for someone with colon cancer (see Ref examples below),
I tried, as soon as DH got the diagnose, to motivate him to also take it. So far he has not been interested :(
It is of course(!) his decision but I think I will try one more time to present research info to him again later.

This is what I was advised to take:
Apex Energetics products - Turmero™ Active and Resvero™ Active
" concentrated source .. in an emulsified, micronized structure.* "
https://www.apexenergetics.com/turmero-active
https://www.apexenergetics.com/resvero-active

I buy the products through a company in UK (I live in Europe), but I believe they order direct from the links/company above. Note: They only sell (most of?) Apex Energetics products to you if you have a health professional you 'go to'.
On my bottle of Turmero it says:
" Amounts per serving (5ml)
Proprietary Blend 420mg
Turmeric Extract (root) (standardized to 95% curcuminoids)
Black Peppar Extract (fruit)"
I take 5ml of the Turmero (+5ml of the Resvero) in a glass of water, before breakfast.
With breakfast I take a few other supplements - a probiotic, some B-vitamins and a joint health product.

Examples of what I have read regarding taking both Curcumin & Resveratrol
Colorectal Cancer: Chemopreventive Role of Curcumin and Resveratrol (2010)
https://www.ncbi.nlm.nih.gov/pubmed/209249
Resveratrol and cancer: Challenges for clinical translation ☆ (2015 )
http://www.sciencedirect.com/science/ar ... 3914003342
DH @65 Emergency colostomy 3/18/16
DX: CC recto-sigmoid junction 4/11
Adenocarcenoma pt 35x15x9mm G3(biopsi) G1(surgical)
Mets:3 Liver resectable
T4aN1bM1a Stage IVa 2/9 Ln
MSS, KRAS-mut G13D
CEA & CA19-9: 5/18 2.5 78 8/17 1.4 48 2/14/17 1.8 29
Chemo: 4 Folfox 6/15-7/30 (b4 liver surgery) 8 after
CT: 8/8 no change
:!: Steroid induced hyperglycemia dx after 3chemo .. hospitalized, insulin -> Metformin
Surgeries (open resections):
3/18 Colostomy 5/23 Primary+gallbl+colostomy reversal (+port) 9/01 Liver mets

.jim.
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Re: Curcumin: What Brand and Where Do You Purchase

Postby .jim. » Sat Mar 18, 2017 11:32 pm

My wife used to go to Dr Brian Lawenda when he was in Las Vegas. He has an integrative oncology web site.

He told us the pepper/'boperine' increases bioavailability by inflammation of the gut that allows the curcumin (and anything else) pass from the gut to the blood supply.

At the time he was recommending Meriva curcumin (any brand).

I shop around (amazon, iherb, vitacost, allstarhealth) to find who has the cheapest.

My wife now takes 2 grams a day... when first diagnosed she took 8 grams.
husband to DW stage IV MSS KRAS-wt BRAF-wt
12-2014 colon resection 2/14 lymph nodes positive
1-2015 cat scan shows liver mets
2-2015 folfox+vectibix
6-2015 remission
11-2015 recurrence to liver
12-2015 switched to folfiri+avastin
5-2016 cea rising, so y90-spheres
7-2016 second half of liver gets y90-spheres
10-2016 cat scan shows liver mets progessing
12-2016 pet scan shows activity in liver and new mets in lungs
1-2017 cea rising; chemo folifiri-avastin stopped
2-2017 TACE and started lonsurf

kiwiinoz
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Re: Curcumin: What Brand and Where Do You Purchase

Postby kiwiinoz » Sun Mar 19, 2017 4:55 pm

I have a simple question. What is the difference between taking curcumin supplements, as compared to actually having turmeric powder?
Stage IV Rectal Cancer (39 Year old male at dx)
pT3N0M1 (wish that was M0)
Diagnosed 05 Dec 2012
LAR 05 Jan 2013
VATS 27 Feb 2013
FOLOFX April 2013 - Sep 2013
Clear Scan 03 Dec 2013 - 12 April 2016
Port Out 26 March 2015

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CRguy
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Re: Curcumin: What Brand and Where Do You Purchase

Postby CRguy » Sun Mar 19, 2017 7:07 pm

concentration, bioavailability and purity of the active ingredients .....

sorry .... in the exec summary mode right now :shock:
got some fires to put out, elsewhere with my forum duties :twisted:

Cheers kiwi
CR
Caregiver twice
Stage IV A rectal cancer/lung met
10 Year survivor
my life is an ongoing NONrandomized UNcontrolled experiment with N=1 !
Review of my Journey so far
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juliej
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Re: Curcumin: What Brand and Where Do You Purchase

Postby juliej » Wed Mar 22, 2017 6:14 pm

kiwiinoz wrote:I have a simple question. What is the difference between taking curcumin supplements, as compared to actually having turmeric powder?

CRguy wrote:concentration, bioavailability and purity of the active ingredients .....

sorry .... in the exec summary mode right now :shock:
got some fires to put out, elsewhere with my forum duties

Kiwi, I will try to answer your question while CRguy, our fearless Zen leader, is off battling forum goblins :twisted: !

The active ingredient in turmeric is curcumin, which is about 2 to 9 percent of turmeric so not very much. The percentage of curcumin varies based on the species, where it is grown, processing (when turmeric rhizomes are heated to produce powder, there is a loss of curcumin), and purity. Adulteration by way of heavy metals, added colors and other contaminants can also be a problem with some turmeric powders (always buy organic). That's not to say turmeric isn't good for you. It is, but in order to achieve a potent, medically advantageous amount, you'd need to consume quite a bit of it every day. Moreover, curcumin supplements have higher absorption/bioavailability, especially when combined with piperine, so you get a lot more impact.

MSKCC has this to say about turmeric and curcumin:

Turmeric: The active constituents are turmerone oil and water-soluble curcuminoids, mainly curcumin which is the focus of most research. In vitro studies suggest that curcumin, the principal bioactive ingredient of turmeric, acts as a weak phytoestrogen (1), and exhibits neuroprotective (2), choleretic (3), anti-inflammatory (4), immunomodulatory (5), anti-proliferative (3), and chemopreventive effects (6) (7) (8). Curcumin, its analogs, and liposomal formulations have also produced chemosensitizing (9) (10) (11) and radiosensitizing effects (12) (13).


Here's the webpage for more info: https://www.mskcc.org/cancer-care/integrative-medicine/herbs/turmeric

Scroll down to the "For Health Care Professionals" section of the webpage and then look under "Clinical Summary" and you'll see all known benefits of tumeric/curcumin.

And here's a great article from the University of Maryland Medical Center about turmeric/curcumin with dosage amounts for turmeric root/powder versus curcumin caps. Check the precaution section to make sure nothing applies to you.

http://umm.edu/health/medical/altmed/herb/turmeric

Hope this helps!
Juliej
Stage IV, liver/lung mets 8/4/2010
Xelox+Avastin 8/18/10 to 10/21/11
LAR, liver resec, HAI pump 11/11
Double lung surgery + ileo reversal 2/12
Adjuvant Xeloda 3-9/12
VATS rt. lung 12/21/12 - benign granuloma!
NED 3/17/12 to 2/20/2017, CEA<1

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CRguy
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Re: Curcumin: What Brand and Where Do You Purchase

Postby CRguy » Wed Mar 22, 2017 10:23 pm

juliej wrote:Hope this helps!
Juliej


"agree with what she said ..... I must
the force is strong with this one
.... mmm "

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:mrgreen:
Cheers
CR
Caregiver twice
Stage IV A rectal cancer/lung met
10 Year survivor
my life is an ongoing NONrandomized UNcontrolled experiment with N=1 !
Review of my Journey so far
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