Xeloda and cardiotoxicity
Xeloda and cardiotoxicity
I am a new member of the club. I have been reading many posts. Thanks for the wealth of information. I started having soreness in my left arm and chest while excercising shortly after starting Xeloda. My oncologist had me take a stress test which resulted in a trip to the ER and an angiogram. The good news is there are non blockages. The bad news is Xeloda and 5FU may be cardio toxic to me. I am hoping just a minor speed bump on my journey. My oncologist is on top of it but I would be interested in hearing from anyone else who has had a similar experience.
Brian 54
7/20/16 Positive FIT
9/27/16 Colonoscopy- dx rectal cancer 5cm, 15cm from AV
10/24/16 EUS T3n2mx
11/7/16 PET scan SUV 16.5. t3n2m0 Staged IIIb
11/14/16 tx neoadjuvant chemo/rad for 28 days, Xeloda
7/20/16 Positive FIT
9/27/16 Colonoscopy- dx rectal cancer 5cm, 15cm from AV
10/24/16 EUS T3n2mx
11/7/16 PET scan SUV 16.5. t3n2m0 Staged IIIb
11/14/16 tx neoadjuvant chemo/rad for 28 days, Xeloda
Re: Xeloda and cardiotoxicity
I've had a number of electrocardiograms in the 6+ years since I finished Xeloda treatment, and results are always OK. I have less energy since completing treatment, but I guess this may be due to ageing. The only residual symptom I still have, is discoloration of the skin on one foot.
Stage 3 R/C -1 node+ ( 7/09)
5 wks radiation, 2 wks chemo: 5FU (8-9/09)
Rectal surgery: tumor removal (11/09)
10 rounds Xeloda: 3000mg/daily 1 wk on/1 wk off (1/10-6/10)
Supplements: Aspirin, Calcium, Vit. D3
03/27/17: 7+ yrs. since surgery--still NED
5 wks radiation, 2 wks chemo: 5FU (8-9/09)
Rectal surgery: tumor removal (11/09)
10 rounds Xeloda: 3000mg/daily 1 wk on/1 wk off (1/10-6/10)
Supplements: Aspirin, Calcium, Vit. D3
03/27/17: 7+ yrs. since surgery--still NED
Re: Xeloda and cardiotoxicity
Interesting you mention this.
I have had a couple of elevated heart rate episodes with the generic Xeloda - 145-155 at rest.
However, the rate comes right down and is always normal when I go to the doc about it.
I have had a couple of elevated heart rate episodes with the generic Xeloda - 145-155 at rest.
However, the rate comes right down and is always normal when I go to the doc about it.
DX Stage 4 2/16 with lung mets
4/16 CT, PET show "marked improvement" in size and number of lung mets, rectal tumor.
8/16 "Great report" from scans, lung mets continue to shrink in size and number, CEA 1.6, cancer "in remission" but surgeon believes tumor remains too large.
10/16 Xrays for constipation problems reveal tumor occupies 25 percent of rectal canal: Occupied 80 percent upon diagnosis 2/16
12/16 Back on Avastin; tumor can be removed, but need better margins.
4/16 CT, PET show "marked improvement" in size and number of lung mets, rectal tumor.
8/16 "Great report" from scans, lung mets continue to shrink in size and number, CEA 1.6, cancer "in remission" but surgeon believes tumor remains too large.
10/16 Xrays for constipation problems reveal tumor occupies 25 percent of rectal canal: Occupied 80 percent upon diagnosis 2/16
12/16 Back on Avastin; tumor can be removed, but need better margins.
Re: Xeloda and cardiotoxicity
I did not have an elevated heart rate but there were abnormal P and T waves on the EKG.
Brian 54
7/20/16 Positive FIT
9/27/16 Colonoscopy- dx rectal cancer 5cm, 15cm from AV
10/24/16 EUS T3n2mx
11/7/16 PET scan SUV 16.5. t3n2m0 Staged IIIb
11/14/16 tx neoadjuvant chemo/rad for 28 days, Xeloda
7/20/16 Positive FIT
9/27/16 Colonoscopy- dx rectal cancer 5cm, 15cm from AV
10/24/16 EUS T3n2mx
11/7/16 PET scan SUV 16.5. t3n2m0 Staged IIIb
11/14/16 tx neoadjuvant chemo/rad for 28 days, Xeloda
Re: Xeloda and cardiotoxicity
I have never taken xeloda but after my second infusion of 5-fu I was sent from the Dr's office to the ER where I was diagnosed with pericarditis. I was experiencing sharp pains in my chest that went through to my back.
My heart rate is always slightly elevated so it really isn't a good indicator for me.
My heart rate is always slightly elevated so it really isn't a good indicator for me.
41 yrs old
Tumor found 9/2015
Surgery 1 - 11/2015 LAR and colostomy
Surgery 2 - 11/2015 wound vac
Surgery 3 - 12/2015 revise resection, move colostomy
Mets to liver - tumor inoperable - one add'l met destroyed
Stage IVa (T3 N2a M1a)
Primary tumor 9 cm x 7.5 cm x 2 cm
Beginning Folfox 1/2016 - Failed
Beginning Folfiri and vectibix 8/2016 — Failed
Beginning Folfirinox + Avastin 11/2016 - Failed
Beginning Keytruda 1/2017
CEA drop from 345 to 7.3 after starting immunotherapy
Lynch positive 3/2016
Tumor found 9/2015
Surgery 1 - 11/2015 LAR and colostomy
Surgery 2 - 11/2015 wound vac
Surgery 3 - 12/2015 revise resection, move colostomy
Mets to liver - tumor inoperable - one add'l met destroyed
Stage IVa (T3 N2a M1a)
Primary tumor 9 cm x 7.5 cm x 2 cm
Beginning Folfox 1/2016 - Failed
Beginning Folfiri and vectibix 8/2016 — Failed
Beginning Folfirinox + Avastin 11/2016 - Failed
Beginning Keytruda 1/2017
CEA drop from 345 to 7.3 after starting immunotherapy
Lynch positive 3/2016
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