I'm new to this so I hope I'm doing it right. My husband has signet ring cell colon with mets to paritoneal cavity. He is MSS. Can anyone offer me any help?
WS, yes, you're doing it right. I asked you in other thread something, to try and see what's available to you (here: viewtopic.php?f=1&t=56992#p450633
). So, asking you again here: Are you saying that it has been determined he is not a HIPEC candidate? And the primary in colon hasn't been removed?
The microsatellite status (MS) is MSS, then. Any other mutations?
Where is he treated, or in which State are you located, if you feel comfortable sharing that? Are you able to travel for treatment...?
For example, there is a clinical trial that I've mentioned in this thread, but who knows if location is not a problem for you.
As Goldfish said, SRC responds to chemo (even if metastatic cancer is not cured by chemotherapy), so maybe other chemo regimen, or an immunotherapy, could convert his cancer to resectable. And you have read that some people has complete responses (that is, no visible cancer) to chemo for peri mets, during many time. Other chemo regimen will be the standard of care offered to your husband.
But knowing if you're husband is treated at a large centre, if his onc talked about clinical trials, how he/she consider them, is important to determine how to help you. There are treatments outside USA, for example, but might be absurd even mention them.