TIL trial - no growth?

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AngelaN
Posts: 206
Joined: Tue Jan 28, 2014 9:00 pm
Facebook Username: angelamnicholas

TIL trial - no growth?

Postby AngelaN » Mon Nov 14, 2016 5:04 pm

Hi,
For those of you who have participated in the TIL trial - is anyone aware of someone whose cells did not grow???? We got a call today that my husband's cells are not growing. Not sure why. Does this happen? Could they just be slow? UGHUGHUGHUGH. Really disappointed. Super really disappointed. Really hoping someone tells me this isn't the end of the road with this trial.
Angie
DH diagnosed with Stage 4 CRC Nov 2013
11 tx Folfox/Avastin; LAR/liver resection/introp RF of liver - May 2014
3 treatments FOLFIRI
Lung resection - Sept 2014
FOLFIRI + Avastin x 10 treatments
Avastin+5FU q3 weeks x 4
SBRT x 1 lung met
RFA for remaining 3 in Oct and Nov
SBRT for liver met Jan 16
lung mets growing
Enrolled in NIH TIL trial Oct 16
XRT for lung met 12/16
Cells didnt grow for TIL trial Feb 17
Waiting for NCT03085914 at Penn

Lee
Posts: 6051
Joined: Sun Apr 16, 2006 4:09 pm

Re: TIL trial - no growth?

Postby Lee » Wed Nov 16, 2016 7:32 pm

Sorry about your recent news. Did DH's doctors give a possible reason for this?

Hope it gets better soon for him.

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 16 years and counting!

User avatar
Maia
Posts: 2443
Joined: Fri Aug 24, 2012 8:00 am

Re: TIL trial - no growth?

Postby Maia » Wed Nov 16, 2016 8:32 pm

Angela, I don't know the answer to your questions but rest reassured that if someone is able to grow TILs in this planet, that is Dr Rosenberg and his team. He's the one who developed a better way for the growth of TILs, which is quite a challenge. So your hubby is on the better hands! : )
If they haven't told you that he is out of the trial, that only can mean that yes, maybe those cells are just slow, IMHO. Hang in there! Strong thoughts going your way.


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