Roche MSS-CRC Immunotherapy Trial Data Pending

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DK37
Posts: 510
Joined: Tue Sep 17, 2013 8:31 am
Location: San Diego

Roche MSS-CRC Immunotherapy Trial Data Pending

Postby DK37 » Thu Oct 20, 2016 8:29 am

A number of MSS-CRC recruiting trials have been announced to have clinical trial data release almost ready for analysis and 1H2017 release. https://twitter.com/AndyBiotech/status/ ... 8818305024

-DK
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/
2016 Colondar 2.0 Model
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ktwmn
Posts: 350
Joined: Tue Aug 02, 2011 9:41 am

Re: Roche MSS-CRC Immunotherapy Trial Data Pending

Postby ktwmn » Thu Oct 20, 2016 11:34 am

Interesting. I just signed consent for one of these trials, Tecentriq (Atezo) and an anti-CEA (has a Roche number). Will be interesting to see what the preliminary results are.
Dx 7/11, Stage IIIc CC
12 txs Folfox 8/2011-2/2012
MSS, KRAS-mut G12D
NED until 3/2015, mets to liver and peritoneum
April-December 2015: 15 txs folfiri+avastin
Liver mets resolved; pelvic met remains
January-May 2016: folfox+avastin; allergic rxn to oxi
June-August 2016: 5FU+avastin
October 2016: looking into immuno trial
January 2017: maintenance chemo xeloda + avastin
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