The Colon Club

THIS IS BIG potential news for the CRC, Lung and Pancreatic cancer worlds. Just announced: the initiation of a KRAS-mutant directed personalized cellular therapy Phase 1 clinical trial for SOME segments of the KRAS-mutant CRC, Lung and pancreatic cancer patient populations - it will depend on the exact mutation and your HLA type. They have not announced the exact mutations or required HLA types yet - but will soon. I will post as soon as available.

The "drugs" will be living immune cells.

It is essentially an effort to commercialize in a more logistically efficient way the NIH TIL trial but limited to only certain slices of patients with certain KRAS-mutations and HLA-types

Expect a lot more info to be coming out soon. From a technology point of view, this is BIG. I'll be writing a science blog about it soon.

I'll announce (and explain) more details as they come out - this is just an exciting teaser press release, but they say trial will start in 2016.

http://www.businesswire.com/news/home/2 ... 006760/en/

Welcome to the future!
-DK37

Thank you for all the work you do to keep us informed. The hope you provide is immeasurable, but we always need to remember you do this work while fighting your own battle. I, for one, am eternally grateful.

Thank you for taking the time and keep us inform!!! Praying that one day soon very soon this will just be like any other health condition.

Yes, thanks!

This is the kind of thing I live for.

Thanks for posting this. I'll be watching for more details on this.

This IS huge my friend !!!

A lot has been discussed in the past about "immune therapies" generally
BUTT not all of the horses in the stable were really ready to run the race

THIS kind of concept IS ready to get into the race
Stay tuned to the future indeed.

Cheers and best wishes
CRguy

Any updates on this trial? Did they ever begin it? Are they still recruiting?

flyboy22 wrote:Any updates on this trial? Did they ever begin it? Are they still recruiting?

The latest (rumor, unofficial) update I heard was about a month ago - saying that the trial was still planned for 2017 but would not start until a bit later in the year.

Cheers,
-DK