As mentioned in previous posts - oncolytic virus therapy has shown potentially some but not clearly high efficacy against CRC in the past but many scientists believe/hope that this treatment modality may be "rescued" by co-dosing with a PD-1 inhibitor.
A new trial has opened up in Indiana to test this hypothesis - they are specifically interested in testing against CRC.
NCT02636036
https://clinicaltrials.gov/ct2/show/NCT ... 036&rank=1
Cheers,
-DK37