Immunotherapy combined with Oncolytic Virus clinical trial

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joe7777777
Posts: 33
Joined: Sat Feb 28, 2015 12:48 pm

Immunotherapy combined with Oncolytic Virus clinical trial

Postby joe7777777 » Sat Jul 02, 2016 7:43 am

Immunotherapy treatment for cancer offers the potential for many different types of combinations since these treatments are less toxic then chemotherapy and radiation


Phase 1 clinical trial to start which combines an oncolytic virus with a PD1 checkpoint inhibitor immunotherapy


http://immuno-oncologynews.com/2016/07/ ... notucirev/


http://www.psioxus.com/psioxus-technology.asp

http://www.businesswire.com/news/home/2 ... y-Clinical

PeterG
Posts: 52
Joined: Tue Feb 03, 2015 12:32 pm

Re: Immunotherapy combined with Oncolytic Virus clinical trial

Postby PeterG » Sat Jul 02, 2016 8:01 am

Is Rhee any indication that this will be tested on folks whose tumors are not MSI-High? Am I conflating the irrelevant? Is this not a checkpoint inhibitor study? Truly interested, and my ignorance was, unfortunately, not entirely assuaged by the articles.
DX Aug. 2013 Resection 09/13.
08/14 CT : .7 CM pulmonary nodule--& multiple nodules.
03/15 15 dendritic cell vaccine-monthly
05/16 begin 3000 MG Xeloda & Avastin
11-16 shrinkage.”Sstable"
2/2017: Port installed. Begin Folfiri and Avastin
8/2017: Xeloda, Avastin and Iranotican. 3-wk cycle.
2-6-18: small pulmonary embolim—some growth in one pulmonary tumor. Start Xarelto.
2-8-18 : Change of chemo: Xeloda with Oxaliplatin no avastin.
9/2018: Tumor growth. Begin Stivarga.

NateA
Posts: 115
Joined: Sun Aug 02, 2015 7:41 pm
Facebook Username: Nathan Drew Allen

Re: Immunotherapy combined with Oncolytic Virus clinical trial

Postby NateA » Sun Jul 03, 2016 5:46 am

Seems like the new drug is a way to heat up the colid tumor i.e. immuno effects. I'm thinking this will be good for MSS patients. I hope!!
7/15 dx CC stage 4 with lots of liver mets CEA 208
KRAS Mutant G12V, MSS.
9/23 from folfoxiri to folfox and Xeloda. CEA 25
11/11/15 all liver markers in the zone, CEA 4.0, moving to Avastin/xeloda for now..tumors shrinking
01/13/16 Avastin/xeloda CEA 3.5
03/11/16 clean PET CEA 4.4


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