New MSS-CRC Immunotherapy Trial: TIL Trial at MD Anderson

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DK37
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Joined: Tue Sep 17, 2013 8:31 am
Location: San Diego

New MSS-CRC Immunotherapy Trial: TIL Trial at MD Anderson

Postby DK37 » Mon May 02, 2016 11:40 am

There are 2 new MSS-CRC immunotherapy trials announced today (neither is recruiting yet - but announced. I'l post as 2 separate posts. Here is #2

#2 - As I promised, the TIL trial for MSS-CRC is expanding beyond the NIH. It has just been announced to begin at MD Anderson in August. I think there will be at least one more site announced in 2016. NCT02757391

https://clinicaltrials.gov/ct2/show/NCT ... 391&rank=1

-DK
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/
2016 Colondar 2.0 Model
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khadars
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Joined: Wed May 04, 2016 2:03 pm
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Re: New MSS-CRC Immunotherapy Trial: TIL Trial at MD Anderson

Postby khadars » Wed May 04, 2016 5:43 pm

DK37, Do you have any idea of where the 2nd TIL site might be? Thanks!
3/2015 - Rectal Cancer @ 26yr old.
5/2015 - Clinical Trial (FOLFOX Only)
9/2015 - LAR with TME (Stage IIIB, RC) w/ Loop Ileostomy
2/2016 - Ileostomy Reversal
5/2016 - Stage IVb

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DK37
Posts: 510
Joined: Tue Sep 17, 2013 8:31 am
Location: San Diego

Re: New MSS-CRC Immunotherapy Trial: TIL Trial at MD Anderson

Postby DK37 » Fri May 06, 2016 6:33 am

khadars wrote:DK37, Do you have any idea of where the 2nd TIL site might be? Thanks!


San Diego - so that will complement MD Anderson in the interior and the NIH on the East Coast.
I think the San Diego site is guaranteed - expected in 2016 but with any construction timeline, that timing could slip (but not by that much).
I do not know for sure the exact cellular immunotherapies San Diego will offer but I believe TIL will be one of them.

-DK
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/
2016 Colondar 2.0 Model
DK37 Science Posts List


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