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AACR-2016 Clinical Trial Post #3: AM0010

Posted: Fri Apr 15, 2016 4:58 pm
by DK37
AACR-2016 Clinical Trial Post #3: AM0010

Clinical trial abstracts of the AACR meeting next week were released this afternoon. AACR presents some clinical trial results - the ASCO conference in June presents much more. A lot of eyes will be on the PD1/Avastin/FOLFOX trial results which will be presented on Monday to see if they mention MSS-CRC. Once I hear feedback what was said, I'll post next week on that one.

Today I'll post (3) clinical trial poster abstracts I noticed with CRC data and with currently open trials.

Title: Anti-tumor activity of PEGylated human IL-10 (AM0010) in patients with advanced solid tumors

Open Trial: https://clinicaltrials.gov/ct2/show/NCT ... 010&rank=1

Mechanism: Immunotherapy

CRC Data: “Prolonged stable disease of 6 or more months was observed in several indications including colon cancer” (doesn’t say if MSS or MSI-high or % of CRC patients showing stable disease)

Side effects: See abstract for details, not being dosed at MTD

Full abstract: http://www.abstractsonline.com/plan/Vie ... 0fb1922267

Re: AACR-2016 Clinical Trial Post #3: AM0010

Posted: Fri Apr 15, 2016 11:53 pm
by Nik Colon
Thanks DK :)