Thank you all for your replies.
Bluebird in answer to your question " if convenient, can you share more info what you have done during this period? how the cancer cells from lymph nodes are removed? by chemo or others?", here goes ":-
I started chemo 3 weeks after surgery (12 rounds of oxaliplaton, 5 F-U and leucovorin) but after 8 rounds my CEA started to rise and a scan at the end of those 12 rounds revealed distant lymph node metastasis to lymph nodes in my abdomen and neck. The following 12 rounds of irinotecan and avastin took care of them after radiation for the neck lymph node and I was NED for 5 months last summer before activity in another lymph node popped up in my sternum, had that radiated with SBRT and was very much hoping that was an oligo metastasis (albeit the 2nd) as everything I have read about that and my radiation oncologist has told me, could be a one off and getting rid of it could mean a cure.
My oncologists at Greenwich Hospital and MSK say that distant lymph node metastasis is very rare as spread to liver and lungs is way more likely but that hasn't been my path so far. (Colon Talk refers to those with distant lymph node metastasis as Olypmians). I think the truth is mine is somewhat aggressive as Folfox failed to work but I'm taking the wack a mole approach and am hoping I can stay ahead and that the cancer eventually gives up!
The reappearance of my cancer in lymph nodes appears to directly correlate with my rise in CEA so am watching that very closely. I'm hoping my recent rise in CEA is related to the inflammation in my chest caused by the neulasta, so will get another blood test next week to check that, fingers crossed.
Somewhat pinning my hopes that the trails for Pembrolizumab will prove my cure in the months to come if Avastin which I am also super confident with doesn't do the trick.
How wonderful to have been NED for a year now, your wife sounds like she have been extremely lucky to have knocked it on the head, am so happy for you both.
Is she still on chemo now?
Dx 3/14. Stage 111b. Aged 51 Mother of 4
3/14 Sigmoidectomy (6 positve lymph nodes out of 15)
12 rounds of oxaliplaton, 5 F-U and leucovorin
9/14 PEP scan tumor in superaclavicular lymph node
1/15 PEP activity in the lymph nodes in abdomen.
12 rounds irinotecan and avastin
9/15 PEP activity in the lymph nodes in sternum
10/15 Radiation SBRT
1/16 PEP activity in another 2 superaclavicular lymph nodes
2/16 irinotecan and avastin
3/16 NED but CEA 6.1