Of course everyone reacts differently. Butt, I have found folfiri to be easier than Folfox. Less fatigue, no neuropathy and no cold sensitivity!
Of course, there is diarrhea. Butt, there's also anti-diarrhea meds. Some folks, by the sounds of it, take 10 pills a day. I typically take 3-5 pills per two weeks. The beginning was worse for me, then I got into the pattern of when I needed which med.
My biggest warning on folfiri - NEVER trust a fart and carry extra underwear.
Stage 3 cc - dx Jan '14 age 53, cea 2.9
t2n2m0, KRAS mutant, MSS
Folfox Feb - Aug '14
Nov '14 cea 27.7 -2 liver masses
Dec '14 left lobectomy and HAI
Jan '15 FUDR and FOLFIRI
Aug '15 fudr done, liver clear, add avastin for lungs. Cea 4.3
Feb '16 CEA rising
May '16 2 wk break then drop Iri for 6 weeks.
Jul '16 cancer grew, constricted main bile duct. Stent inserted. On break till jaundice clears. CEA climbing. Doing reduced Folfox. Allergic to Oxali.
Sep'16 chemo failed. Trial or hospice?