NEJM: Potential Stage 2 CRC Biomarker for Chemotherapy Use
Posted: Fri Jan 22, 2016 7:35 am
by DK37
A potentially very important new finding showing a biomarker that appears predictive of Stage 2 patients that would significantly benefit from chemotherapy. Findings were based upon retrospective analysis, prospective clinical trials have not been done yet. First link = news article. Second link = article from the New England Journal of Medicine.
http://www.medscape.com/viewarticle/857470 and
http://www.nejm.org/doi/full/10.1056/NEJMoa1506597-DK
Re: NEJM: Potential Stage 2 CRC Biomarker for Chemotherapy Use
Posted: Fri Jan 22, 2016 7:11 pm
by Nik Colon
Just wanted to say hi, and thanks again for all your info. I see you're keeping your list updated
Thanks again for all you do.
Nik
Re: NEJM: Potential Stage 2 CRC Biomarker for Chemotherapy Use
Posted: Fri Jan 22, 2016 10:57 pm
by DK37
Nik Colon wrote:Just wanted to say hi, and thanks again for all your info. I see you're keeping your list updated
Thanks again for all you do.
Nik
Hi Nik! I thought of you this morning when I was adding this link to my list you started!
-DK
Re: NEJM: Potential Stage 2 CRC Biomarker for Chemotherapy Use
Posted: Fri Jan 22, 2016 11:31 pm
by Nik Colon
DK37 wrote:Nik Colon wrote:Just wanted to say hi, and thanks again for all your info. I see you're keeping your list updated
Thanks again for all you do.
Nik
Hi Nik! I thought of you this morning when I was adding this link to my list you started!
-DK
hope you are doing well
Re: NEJM: Potential Stage 2 CRC Biomarker for Chemotherapy Use
Posted: Sat Jan 23, 2016 1:54 am
by orcasres
DK,
Thanks so much for posting this. I was staged IIA but I got adjuvant chemo because my tumor was medullary which is rare and I had lymphovascular invasion. The medullary tumor was the driver. I just pulled my pathology report and I was CDX2 positive. While I have a number of residual side effects from the chemo and I wanted to take every step I could to keep the disease from returning (I never regretted doing it), I wonder with this study if it would have been recommended. I am thrilled to see this kind of research. It certainly seems like it will put another tool in the box for stage II folks.
Lois