tumor budding present

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Talib
Posts: 20
Joined: Tue Dec 08, 2015 2:57 pm
Facebook Username: Tali Bellish
Location: Israel

tumor budding present

Postby Talib » Wed Dec 30, 2015 1:53 pm

Hi,
Does anyone knows what "tumor budding present" means and what are the implications of it?
It is stated in my Biopsy next to level of differentiation.

Thanks,
Tali
colon cancer - June 2015
45 yrs old at diagnosis
stage III B- 2/32 lymph nodes positive
surgery - July 2015
chemo - FOLFOX August 15 - Feb 16
Feb 16 Pet CT - NED
Sep 16 CT - NED
Jan 17- CT - NED
May 17 liver ultrasound - clear
Nov 17 CT - NED
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Fluff Bottom
Posts: 77
Joined: Fri Oct 23, 2015 8:13 am

Re: tumor budding present

Postby Fluff Bottom » Wed Dec 30, 2015 3:21 pm

http://www.nature.com/modpathol/journal ... 1294a.html

Tali, I don't have an answer but this link explains it pretty well.
10/26/15-Colonoscopy-Mass in Sigmoid
adenocarcinoma mucinous type components.
Lynch Neg
Stage IIIb-T3N1c, 3/13 nodes, High Grade-Poorly Diff to Undiff
12/16/15-Port, FOLFOX
12 rounds FOLFOX 5/22/16
5/22/18-Clear CT
9/6/18-CT for possible hernia=mets
9/18/18 PET mets to lungs, liver, peri
10/23/18-rapid growth of mets
BRAF V600, KRAS Wild, MSS
Back on FOLFOX=reaction
FOLFIRI until it failed
Tafinlar/Mekinist=Kidney Failure
Mets to uterus, adrenal gland
Low dose Stivarga/Opdivo. Possible liver toxicity.
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