Keytruda FDA Breakthrough Therapy Designation for MSI-High CRC

[DK37]

As expected... with this high of response rate of PD-(L)1 inhibitors in MSI-CRC, Merck's version got a Breakthrough Therapy Designation from the FDA~ http://www.businesswire.com/news/home/2 ... -U.S.-Food

-DK

[daisydaisy]

You posted about it in May - wow! By the way, I made a search here about keytruda, and one member, MikeW mentioned that he worked for Merck.
It is amazing to observe how promising drugs are being developed. And thank you, as usual, for providing us with this info!

[ieowi]

Thank youUUUUUuUUUUUUuUUUUuuuuuuUuuuu DK37
Now let's hope something work out for MSS MSI-LOW

[DK37]

You posted about it in May - wow! By the way, I made a search here about keytruda, and one member, MikeW mentioned that he worked for Merck.
It is amazing to observe how promising drugs are being developed. And thank you, as usual, for providing us with this info!

When another PD-1 inhibitor submitted for FDA approval (for lung cancer) - the FDA approved it in 4 DAYS. If the preliminary data in MSI-high CRC repeats in the larger trial in progress (which at least roughly I think it probably will) - I expect a very fast approval decision for MSI-high CRC. Immunotherapies have changed everything in oncology drug development... Now hopefully MSS-CRC's turn some time soon!

-DK

[Nik Colon]

Now hopefully MSS-CRC's turn some time soon!

-DK

Yes, I hope so too!