Just curious if anyone has ever had problems with their voice box/vocal cords? I have mouth sores, and my tongue feels like it's burnt, but have also had issues with my voice for 3 days now and it's not getting any better.
DOC looked at it yesterday, said it was just post-nasal drainage, but 3 days???
Voice issues - Erbitux - FOLFIRI
Voice issues - Erbitux - FOLFIRI
58 yo female
Dx CRC 2/17/14
perm colostomy 3/14
12 rounds 5FU
Small bowel obstruction 8/14
Multiple nodules both lungs 6/15
FOLFIRI + ERBITUX started 8/11/15
Irinotecan reduced 40% , October
12/15 NED, holiday next 2 treatments, then 5FU only
Mets are back 3/16
Erbitux + Irinotecan only; dropping 5FU
CT Scan 6/16 shows mets still there
5/17 been on Erbitux only
chemo break for 3 months
5 mets now on CT Scan. Back to Erbitux
1/18 lung Mets all increased slightly
Adding Irinotecan back
Dx CRC 2/17/14
perm colostomy 3/14
12 rounds 5FU
Small bowel obstruction 8/14
Multiple nodules both lungs 6/15
FOLFIRI + ERBITUX started 8/11/15
Irinotecan reduced 40% , October
12/15 NED, holiday next 2 treatments, then 5FU only
Mets are back 3/16
Erbitux + Irinotecan only; dropping 5FU
CT Scan 6/16 shows mets still there
5/17 been on Erbitux only
chemo break for 3 months
5 mets now on CT Scan. Back to Erbitux
1/18 lung Mets all increased slightly
Adding Irinotecan back
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midlifemom
- Posts: 1358
- Joined: Wed Jan 15, 2014 10:58 am
- Location: NJ
Re: Voice issues - Erbitux - FOLFIRI
My voice gets funny, sorta high pitched and squeaky. This has been going on for a few months. My onc said it's not unusual. It is worse when I'm tired.
Stage 3 cc - dx Jan '14 age 53, cea 2.9
t2n2m0, KRAS mutant, MSS
Folfox Feb - Aug '14
Nov '14 cea 27.7 -2 liver masses
Dec '14 left lobectomy and HAI
Jan '15 FUDR and FOLFIRI
Aug '15 fudr done, liver clear, add avastin for lungs. Cea 4.3
Feb '16 CEA rising
May '16 2 wk break then drop Iri for 6 weeks.
Jul '16 cancer grew, constricted main bile duct. Stent inserted. On break till jaundice clears. CEA climbing. Doing reduced Folfox. Allergic to Oxali.
Sep'16 chemo failed. Trial or hospice?
t2n2m0, KRAS mutant, MSS
Folfox Feb - Aug '14
Nov '14 cea 27.7 -2 liver masses
Dec '14 left lobectomy and HAI
Jan '15 FUDR and FOLFIRI
Aug '15 fudr done, liver clear, add avastin for lungs. Cea 4.3
Feb '16 CEA rising
May '16 2 wk break then drop Iri for 6 weeks.
Jul '16 cancer grew, constricted main bile duct. Stent inserted. On break till jaundice clears. CEA climbing. Doing reduced Folfox. Allergic to Oxali.
Sep'16 chemo failed. Trial or hospice?
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Redwingfan3991
- Posts: 25
- Joined: Wed Jun 04, 2014 6:17 pm
- Location: DTW
Re: Voice issues - Erbitux - FOLFIRI
On Folfori and Stivarga my mom sounded like she had a permanent case of larangitis. Now that's she's done with chemo her voice has come back
Daughter/caregiver to mom aged 64
Kras mutant
4/14 diagnosed stage IV colon cancer mets to omentum
5/14 started folfox & avastin
10/14 chemo not working tumors growing
11/14 laparoscopic surgery to see how much seeding
12/14 unable to do surgery
1/15-8/15 folfiri
8/15- folfiri fail
10/15- Stivarga Stopped after 9 days due to side effects
10/15-- maybe clinical trial ? All conventional options seem to be exhausted
12/15--2/16 clinical trail failed
4/16 LONSURF
Kras mutant
4/14 diagnosed stage IV colon cancer mets to omentum
5/14 started folfox & avastin
10/14 chemo not working tumors growing
11/14 laparoscopic surgery to see how much seeding
12/14 unable to do surgery
1/15-8/15 folfiri
8/15- folfiri fail
10/15- Stivarga Stopped after 9 days due to side effects
10/15-- maybe clinical trial ? All conventional options seem to be exhausted
12/15--2/16 clinical trail failed
4/16 LONSURF
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Bev G
- Posts: 5856
- Joined: Thu Jan 07, 2010 11:19 pm
- Facebook Username: Bev Golde
- Location: Quechee, VT
Re: Voice issues - Erbitux - FOLFIRI
Yeah, I had a really raspy voice/laryngitis on FOLFIRI. It went away when chemo ended.
58 yo Type1 DM 48 years
12/09 Stage IV 2/22 nodes + liver met, colon resec
3 tx FOLFIRI, liver resec 4/10
9/10 6 mos off chemo, Neg PET&CTC CEA nl
2/11 finished total 10 rounds chemo
9/13 ^17th clean PET/CT NED for now
12/09 Stage IV 2/22 nodes + liver met, colon resec
3 tx FOLFIRI, liver resec 4/10
9/10 6 mos off chemo, Neg PET&CTC CEA nl
2/11 finished total 10 rounds chemo
9/13 ^17th clean PET/CT NED for now
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Joannerogers
- Posts: 260
- Joined: Tue Jun 16, 2015 4:50 pm
Re: Voice issues - Erbitux - FOLFIRI
I was on folfox and my voice would get horse, especially the more tired I got.
53yo married 27 years, 2 children, 24 and 25
Diagnosed april 23,2015 rectosigmoid
Starting CEA 1845
Port placement and liver bx April 27
Folfox started april 29
Avastin added on May 6
Stage IV crc with mets to 50% of liver
10/13/15 dc'd transfusion #12...toxic
Pet/ct scan on 11/3/15
20% liver resected all margins clear 11/30/15
8/18/15 cea 21.
9/15/15 cea 13.9
10/13/15 cea 14.4
1/22/2016 cea 2.5
LAR 02/15/16 all clear
Diagnosed april 23,2015 rectosigmoid
Starting CEA 1845
Port placement and liver bx April 27
Folfox started april 29
Avastin added on May 6
Stage IV crc with mets to 50% of liver
10/13/15 dc'd transfusion #12...toxic
Pet/ct scan on 11/3/15
20% liver resected all margins clear 11/30/15
8/18/15 cea 21.
9/15/15 cea 13.9
10/13/15 cea 14.4
1/22/2016 cea 2.5
LAR 02/15/16 all clear
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Nik Colon
Re: Voice issues - Erbitux - FOLFIRI
I have no idea, but just thinking here. If you think about having a cold and soreness or dryness that happens...maybe it's similar?
Re: Voice issues - Erbitux - FOLFIRI
I'm on Folfox so I don't think I really can contribute properly 
, but I sounded like a boy whose voice was breaking for the first two days of this week's round (my second). It freaked me out a little bit, to be honest.
Interesting that it is perhaps not the Oxi, though.
As if there aren't enough weird chemo side effects...
, but I sounded like a boy whose voice was breaking for the first two days of this week's round (my second). It freaked me out a little bit, to be honest.Interesting that it is perhaps not the Oxi, though.
As if there aren't enough weird chemo side effects...
Last edited by Lisa90 on Thu Oct 29, 2015 3:03 pm, edited 1 time in total.
25y/o F
Symptom onset Aug '14
Colonoscopy done 1 Sep '15
Emergency colectomy done 2 Sep '15 due to obstructing tumor
DX CC stage IIIB - Sigmoid Colon (Adenocarcinoma)
FOLFOX started 13 Oct '15
Oxaliplatin dropped at treatment 9
Treatment completed 5 May '16
Li-Fraumeni syndrome confirmed
Previous history:
- Rhabdomyosarcoma ('92) Right leg
- Osteosarcoma ('01) Right leg
- Osteosarcoma ('12) Left leg (recurred '14)
Symptom onset Aug '14
Colonoscopy done 1 Sep '15
Emergency colectomy done 2 Sep '15 due to obstructing tumor
DX CC stage IIIB - Sigmoid Colon (Adenocarcinoma)
FOLFOX started 13 Oct '15
Oxaliplatin dropped at treatment 9
Treatment completed 5 May '16
Li-Fraumeni syndrome confirmed
Previous history:
- Rhabdomyosarcoma ('92) Right leg
- Osteosarcoma ('01) Right leg
- Osteosarcoma ('12) Left leg (recurred '14)
Re: Voice issues - Erbitux - FOLFIRI
My mother has got this weird side effect. Her voice sounds like she had more testosterone.
care giver to mom 68 y/o
2002: right breast cancer stage II 2cm, 4/19 ln,
mastectomy
chemo: 4xdox+4xtax+4xcmf
2013: left bc stage I 1 cm, lymph nodes clear,
mastectomy, tamoxifen
8/15 sigmoid colon cancer stage IV,
5 cm, unresectable/fixed to the wall,
kras mut codon 13
lvr met 13 mm, peritoneal carcinomatosis, CEA 1440
8/15 folfiri started
10/15 CEA 1071 switched to folfox
2002: right breast cancer stage II 2cm, 4/19 ln,
mastectomy
chemo: 4xdox+4xtax+4xcmf
2013: left bc stage I 1 cm, lymph nodes clear,
mastectomy, tamoxifen
8/15 sigmoid colon cancer stage IV,
5 cm, unresectable/fixed to the wall,
kras mut codon 13
lvr met 13 mm, peritoneal carcinomatosis, CEA 1440
8/15 folfiri started
10/15 CEA 1071 switched to folfox
Re: Voice issues - Erbitux - FOLFIRI
Yes! My voice gets raspy and sometimes almost nothing comes out. It's not all the time, but it's weird. I didn't really attribute it to chemo, but of course it is.
47 yo Husband and Father of 13 yo son and 11 yo daughter
DX 4/9/2015 - Rectal Cancer stage 3c
Radiation/Xeloda started 5/6/2015, ended 6/15/2015
APR Surgery 8/14/2015
Folfox started 8/23/2015
DX 4/9/2015 - Rectal Cancer stage 3c
Radiation/Xeloda started 5/6/2015, ended 6/15/2015
APR Surgery 8/14/2015
Folfox started 8/23/2015
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