DK37 Science Posts List

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DK37
Posts: 502
Joined: Tue Sep 17, 2013 8:31 am
Location: San Diego

DK37 Science Posts List

Postby DK37 » Tue Oct 20, 2015 10:26 pm

Following a suggestion/request from Nik - here is a list of links to the various science post threads I've started since I started posting on Colon Talk in last 2014.

I'll try (hard) to remember to update it with new links when I make new posts.

Up to you guys if you think it is useful or not... THANK YOU NIK for compiling this starter list for me! It's in chronological order.

Cheers,
-DK

Nov 25, 2014
New CRC Immunotherapy Trial Announced: anti-PD1 + anti-CSF1R
viewtopic.php?f=1&t=48812&p=371077#p371077

Jan 09, 2015
Forbes - Immuno-oncology Story
viewtopic.php?f=1&t=49692&p=377425#p377425

Feb 20, 2015
New CRC Immunotherapy Paper: PD-L1 + ITK Inhibitors
viewtopic.php?f=1&t=50318&p=385011#p385011

Feb 27, 2015
Advance Screening - Emperor of All Maladies (Ken Burns)
viewtopic.php?f=1&t=50399&p=386106#p386106

Mar 16, 2015
New Pilot Clinical Trial Results for BRAF-mut Stage IV CRC
viewtopic.php?f=1&t=50572&p=388522#p388522

Mar 18, 2015
RRx-001 Prelim. Phase 2 Data - Resensitizing Tumors to chemo
viewtopic.php?f=1&t=50598&p=388897#p388897

Mar 23, 2015
Updated RRx-001 Preliminary Phase 2 Trial Data
viewtopic.php?f=1&t=50662&p=389876#p389876

Apr 19, 2015
Johns Hopkins Immunotherapy Paper: 100% CRC cure rate in a poorly immunogenic CRC Mouse Model
viewtopic.php?f=1&t=51103&p=394260#p394260

Apr 25, 2015
New Arizona Trial: Nivolumab (PD-1 Immunotherapy) + XELIRI/Irinotecan
viewtopic.php?f=1&t=51169&p=395429#p395429

Apr 27, 2015
Update on MGD007 Trial – New Sites Open!
viewtopic.php?f=1&t=51205&p=395783#p395783

May 17, 2015
KRAS-wt: Clinical Trial Results for Sym004 (after cetuximab resistance)
viewtopic.php?f=1&t=51417&p=398909#p398909

May 29, 2015
Potential to be Biggest CRC Drug Breakthrough in Years (ASCO Results - PD1 for MMR-deficient CRC)
viewtopic.php?f=1&t=51551&p=400371#p400371

Jun 27, 2015
My Blood Biopsy Story (From Voxx66's News from Dr appt post)
viewtopic.php?f=1&t=51860&p=404644#p404644

Jul 07, 2015
Preliminary Clinical Trial Data for "Xilonix" - Currently in Phase 3 Trials for mCRC
viewtopic.php?f=1&t=51936&p=405574#p405574

Jul 14, 2015
New Monthly DK Column: The Currently Incurable Scientist
viewtopic.php?f=1&t=52004&p=406248#p406248

Jul 24, 2015
The Currently Incurable Scientist: Turning a Cold CRC Tumor Hot
viewtopic.php?f=1&t=52072&p=407081#p407081

Aug 08, 2015
Anti-4-1BB (CD137) Immunotherapy - e.g. Urelumab CRC Trial
viewtopic.php?f=1&t=52176&p=408263#p408263

Aug 13, 2015
The Currently Incurable Scientist: The Future of anti-EGFR Therapy?
viewtopic.php?f=1&t=52242&p=408851#p408851

Aug 18, 2015
Pushing for Lung RFA & the Power of Hope
viewtopic.php?f=1&t=52286&p=409394#p409394

Aug 20, 2015
RRx-001 Phase 1 Clinical Trial Results Published in Lancet Oncology
viewtopic.php?f=1&t=52306&p=409612#p409612

Aug 21, 2015
Anti-Immunosuppression PD-1 Co-therapies for CRC (Reply to Jortego128’s Bavituximab for Rectal Adenocarcinoma... post)
viewtopic.php?f=1&t=52315&p=409674#p409674

Aug 31, 2015
New PD-1 Inhibitor Combo Studies for CRC (All or MSS Specific)
viewtopic.php?f=1&t=52397&p=410649#p410649

Sep 08, 2015
Immunotherapy Suggestion: Add MSI/MSS Status to Your Signature Line (Explained)
viewtopic.php?f=1&t=52480&p=411684#p411684

Sep 15, 2015
Currently Incurable Scientist: Putting out the Inflammation Fire (Xilonix)
viewtopic.php?f=1&t=52534&p=412532#p412532

Sep 22, 2015
TAS-102 FDA Approved!
viewtopic.php?f=1&t=52603&p=413564#p413564

Oct 01, 2015
Neon Therapeutics - TIL ImmunoTherapy
viewtopic.php?f=1&t=52682&p=414496#p414496

Oct 11, 2015
Sneak Peek - Major MSI Education Project
viewtopic.php?f=1&t=52741&p=415285#p415285

Oct 13, 2015
The Currently Incurable Scientist:Releasing the PD-1 Brakes in MSI-High CRC Patients
viewtopic.php?f=1&t=52758&p=415479#p415479

Oct 14, 2015
The Faces of Successful Colorectal Cancer Immunotherapies Vol. 1
viewtopic.php?f=1&t=52772&p=415599#p415599

Oct 17, 2015
FPA008 (anti-CSF1r) + PD-1 Inhibitor Deal Announced (Trial Already Started)
viewtopic.php?f=1&t=52787&p=415815#p415815

Oct 18, 2015
MSS-CRC Immunotherapy Phase 1 Trial at Johns Hopkins (PD-1 + Epigenetic Drugs)
viewtopic.php?f=1&t=52799&p=415959#p415959

Nov 2, 2015
Two more PD-(L)1 Combo Trials Hoped to Make MSS-CRC Tumors "Hot" Towards the Immune System (IDO1 & CD73)
viewtopic.php?f=1&t=52938

Nov 9, 2015
Impacts of Gut Bacteria (probiotics) on Immune Response to Tumors - anti-PD(L)1 Synergy but also taken alone.
viewtopic.php?f=1&t=53006&p=418204#p418204

Nov 17, 2015
The Currently Incurable Scientist: REPROGRAMMING A TUMOR FOR DEATH (RRx-001)
viewtopic.php?f=1&t=53072

Nov 24, 2015
RRx-001 Phase 2 Trial: New East Coast Site
viewtopic.php?f=1&t=53122&p=419630#p419630

Dec 6, 2015
Merck (anti-PD-1) + Amgen (anti-CSF1R) CRC Immunotherapy Trial Announcement
viewtopic.php?f=1&t=53218

Jan 12. 2016
BMS (major Opdivo & Yervoy immunotherapy company) announces their 2016 strategic plans, including MSS-CRC at the JP Morgan Healthcare company
viewtopic.php?f=1&t=53460

Jan 15, 2016
New Immunotherapy Combo Trial Open to both MSI-high & MSS CRC (CPI-444; adenosine-A2A combo)
viewtopic.php?f=1&t=53472

Jan 22, 2016
Potential new biomarker to identify Stage 2 CRC patients who would benefit from chemotherapy
viewtopic.php?f=1&t=53523

Jan 25, 2016
New MSS CRC Phase 1 Trial: PF-06671008 (P-cadherin targeting)
viewtopic.php?f=1&t=53552

Jan 28, 2016
BBI-608 Clinical Trial Update
viewtopic.php?f=1&t=53576

Feb 4, 2016
Personalized Immunotherapy: Therapeutic Vaccines
viewtopic.php?f=1&t=53635

Feb 6, 2016
New MSS-CRC Immunotherapy Trial: JNJ-61610588 (anti-VISTA)
viewtopic.php?f=1&t=53643

Feb 10, 2016
MSS-CRC Immunotherapy Trial: AM0010
viewtopic.php?f=1&t=53677

Feb 15, 2016
For KRAS-Mutant CRC: PD-1 Combination Trial with cobimetinib (MEK inhibitor)
viewtopic.php?f=1&t=53710

Feb 26, 2016
DK's Personal Cancer Research Science Project
viewtopic.php?f=1&t=53792

March 19, 2016
New MSS Trial: anti-CSF1R "AMG 820" + anti-PD1
viewtopic.php?f=1&t=54065

March 19, 2016
MSS Trial: Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab)
viewtopic.php?f=1&t=54066

April 4, 2016
Crowdfunding a New CRC Trial at UCSD (Pulse High Dosed erlotinib)
viewtopic.php?f=1&t=54242

April 8, 2016
CCR2 Antag Clinical Immunotherapy Activity Against a "Cold" Tumor Type (Not CRC but Keep Reading!)
viewtopic.php?f=1&t=54282

April 15, 2016
AACR-2016 Clinical Trial Poster Abstracts: IMMU-130, CFI-400945, AM0010
viewtopic.php?f=1&t=54336

viewtopic.php?f=1&t=54337

viewtopic.php?f=1&t=54338

April 20, 2016
AACR-2016 Trial Data Release + 1st MSS-CRC Combo-Immunotherapy Trial Results Announcement for ASCO-2016
viewtopic.php?f=1&t=54391

May 2, 2016
New MSS-CRC Immunotherapy Trial - PDL1/CTLA4/FOLFOX - Liver-only Mets
viewtopic.php?f=1&t=54518

New MSS-CRC Immunotherapy Trial: TIL Trial at MD Anderson
viewtopic.php?f=1&t=54519

May 3, 2016
New MSS-CRC Immunotherapy Trial: Erbitux+Keytruda
viewtopic.php?f=1&t=54525

May 18, 2016
BIG (BIG!) MSS-CRC Immunotherapy News Out of ASCO! (MEKi + PDL1i)
viewtopic.php?f=1&t=54674

May 20, 2016
French MSS-CRC Trial (PDL1 + anti-CSF1R)
viewtopic.php?f=1&t=54684

May 24, 2016
MDA Personalized Therapeutic Vaccine Now Recruiting
viewtopic.php?f=1&t=54713

May 31, 2016
New MSS-Elegible PDL1 Combo Trial (RO6895882, CEA-targetted IL2)
viewtopic.php?f=1&t=54774

June 2, 2016
READ! PHASE 3 MSS-CRC Immunotherapy Trial Just Registered!! (Cobi + Atezo)
viewtopic.php?f=1&t=54792

June 5, 2016
Today's ASCO-2016 Oral Presentation on MSS-CRC PDL1-MEK Immunotherapy Success
viewtopic.php?f=1&t=54825

June 5, 2016
ASCO-2016: Updated PD1 vs PD1-CTLA4 Immunotherapy for MSI-high CRC
viewtopic.php?f=1&t=54816

June 11, 2016
Global Randomized Phase 3 Clinical Trial for BRAF-mut CRC
viewtopic.php?f=1&t=54874

June 15, 2016
Phase 2 Clinical Trial: BAX69 + either 5-FU or Panitumumab SoC
viewtopic.php?f=1&t=54924

June 15, 2016
BRAF-Mutant Small Bowel Cancer (or other rare cancers)
viewtopic.php?f=1&t=54925

June 15, 2016
New RRx-001 Non-Randomized Trial (Northern CA & NJ)
viewtopic.php?f=1&t=54933

June 24, 2016
Interview with Clinical Trial Principal Investigator of MSS-CRC MEK-PDL1 Immunotherapy Breakthrough
viewtopic.php?f=1&t=55021&p=436044#p436044

August 3, 2016
MSS-CRC: New Oncolytic Virus + PD1 Inhibitor Trial
viewtopic.php?f=1&t=55358

August 7, 2016
Combination of radiotherapy (radiation) with PD1 immunotherapy in MSS-CRC
viewtopic.php?f=1&t=55393

August 19, 2016
New MSS-CRC PD1 Immunotherapy Trial in MINNESOTA
viewtopic.php?f=1&t=55522

August 19, 2016
Cleveland Clinic: New CRC Targeted Therapy Trial
viewtopic.php?f=1&t=55523

September 2, 2016
Immunotherapy Trial: Patients WITH Brain Metastases
viewtopic.php?f=1&t=55812

September 18,2016
New MSS-CRC Immunotherapy Trial: Arginase Inhibitor CB-1158
viewtopic.php?f=1&t=55940

September 23, 2016
Big Trial Announcement: MSS-CRC/KRAS-Mut TCR Cellular Immunotherapy Trial from Kite Pharma
viewtopic.php?f=1&t=55999

September 26, 2016
***My personal project***
STAT NEWS: A CANCER RESEARCHER RACES TO FIND A [MSS-CRC] CURE — FOR HIS OWN INCURABLE CANCER
viewtopic.php?f=1&t=56022

September 27, 2016
MSS-CRC: PD1/NKTR-214 Combo Trial Announcement
viewtopic.php?f=1&t=56031

September 29, 2016
Fasting and Chemo: My Take on It
viewtopic.php?f=1&t=56049

October 1, 2016
Citizen Science: Reporting of FASTING and Chemo Results
viewtopic.php?f=1&t=56080

October 16, 2016
***My Personal Trial***
DK37's FIRST MSS-CRC IMMUNOTHERAPY CLINICAL TRIAL (ONCOLYTIC VIRUS + PD1)
viewtopic.php?f=1&t=56213

November 4, 2016
Big New MSS-CRC Immmunotherapy Trial: anti-CD47
viewtopic.php?f=1&t=56383

November 19, 2016
Peri Mets / MSS-CRC Immunotherapy Trial (Oncolytic Virus + anti-PDL1)
viewtopic.php?f=1&t=56499

November 20, 2016
A Potential MSS-CRC Immunotherapy From an AIDS Drug Start: The CCR5 Receptor Antagonist Maraviroc
viewtopic.php?f=1&t=56503

December 7, 2016
MSS-CRC Trial: Phase 2 Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer
viewtopic.php?f=1&t=56606

December 7, 2016
MSS-CRC Immunotherapy Trial: CEA-CD3 Bifunctional + PDL1 Inhibitor
viewtopic.php?f=1&t=56607

January 4, 2017
DK37's Personal BIG PICTURE Opinions on CLINICAL TRIALS
viewtopic.php?f=1&t=56838

July 6, 2017
My personal choice for best ASCO-2017 MSS CRC Clinical Trial and Presentation
viewtopic.php?f=1&t=58347
Last edited by DK37 on Thu Jul 06, 2017 3:38 pm, edited 57 times in total.
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://colorectalmsstrials.org/
2016 Colondar 2.0 Model
DK37 Science Posts List

User avatar
DK37
Posts: 502
Joined: Tue Sep 17, 2013 8:31 am
Location: San Diego

Re: DK37 Science Posts List

Postby DK37 » Sat Jan 30, 2016 10:27 pm



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