I really hope they find something for mss/msi-low, I had a chat with a research doctor in MDA he mentioned that they are heavily focused on MSI-High as they can do something for them
But he also said don't worry we are after mss but until now nothing has showed up with significant results as DK37 mentioned.
I also need to mention doing cms 400 test is a very good handy thing to keep around. You never know what you could find in it, preferably do it in foundation medicine a friend did two cms 400 tests one at MDA and another in foundation medicine his oncology said the foundation medicine show much more details and there were some differences !
I currently requested to do it .at foundation medicine of course. And they also do PD-l1 Test !!!!
Father 58 yo , Colon cancer IV + 4 Lymph. 7/2015
K-ras Mutant,GNAS,FBXW7,PIK3CA, MSI-low
4 cycles irinotecan+FU5
developed abdominal met + lung met...Failed
4 cycle Oxaliplatin+folfox. peri met growing...Failed
unofficial trial !!!